نتایج جستجو برای: pyrvinium pamoate
تعداد نتایج: 257 فیلتر نتایج به سال:
Constitutive WNT activity drives the growth of various human tumors, including nearly all colorectal cancers (CRCs). Despite this prominence in cancer, no WNT inhibitor is currently approved for use in the clinic largely due to the small number of druggable signaling components in the WNT pathway and the substantial toxicity to normal gastrointestinal tissue. We have shown that pyrvinium, which...
The FDA is investigating the unexplained deaths of 2 patients who received intramuscular injections of olanzapine pamoate (Zyprexa Relprevv). The patients died 3–4 days after receiving appropriate doses of the drug, and both patients were found to have very high olanzapine blood levels after death. High doses of olanzapine can cause delirium, cardiopulmonary arrest, cardiac arrhythmias, and red...
A second polymorphic form of a 1 : 2 : 3 pamoate : DABCO : water salt has been obtained by liquid-assisted grinding, and it is shown that interconversion between this salt and a salt with 1 : 1 : 2 stoichiometry is facile via liquid-assisted grinding with additional amounts of pamoic acid (to generate the 1 : 1 : 2 salt) or DABCO (to generate the 1 : 2 : 3 salt).
n engl j med 370;20 nejm.org may 15, 2014 1954 transmitted helminth infections: systematic review and metaanalysis. JAMA 2008;299:1937-48. 3. Keiser J, Tritten L, Silbereisen A, Speich B, Adelfio R, Vargas M. Activity of oxantel pamoate monotherapy and combination chemotherapy against Trichuris muris and hookworms: revival of an old drug. PLoS Negl Trop Dis 2013;7(3):e2119. 4. Nagpal S, Sinclai...
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