The in vitro activity of rac-mefloquine hydrochloride and its pure enantiomers was tested against a chloroquine-resistant (PF.IBS2) strain of Plasmodium falciparum. The parasite isolated from Iranian patients was cultured in vitro by the candle jar method described by Tranger and Jensen and was exposed to the racemic mefloquine or its enantiomers over the concentration range of 10-9 to 10-4 M. ...

Arsenate was produced when anoxic Mono Lake water samples were amended with arsenite and either selenate or nitrate. Arsenite oxidation did not occur in killed control samples or live samples with no added terminal electron acceptor. Potential rates of anaerobic arsenite oxidation with selenate were comparable to those with nitrate ( approximately 12 to 15 mumol.liter(-1) h(-1)). A pure culture...

BACKGROUND Optically pure acetoin (AC) is an important platform chemical which has been widely used to synthesize novel optically active α-hydroxyketone derivatives and liquid crystal composites. RESULTS In this study, slaC and gldA encoding meso-2,3-butanediol dehydrogenase (meso-2,3-BDH) and glycerol dehydrogenase (GDH), respectively, in S. marcescens MG1 were knocked out to block the conve...

The mechanical behavior and microstructure of pure iron subjected to dominant shear loading has been characterized over a wide range of train rates. Pure iron is found to be highly strain-rate sensitive. Iron exhibits marked strain softening at ε̇ ≈ 8000 s−1 − σ ≈ 850 MPa that is nexpected for the annealed material, as characterized by TEM, but is identical to that of iron preshocked at 40 GPa [...

In this article, ZnO and ZnO:Mn nanoparticles prepared by reverse micelle method. The various crystalline properties of these nanoparticles such as size, d-spacing, strain, stress, dislocation density and texture coefficient have been calculated with the help of XRD spectrum. The XRD results indicated that the synthesized ZnO and ZnO:Mn nanoparticles have a pure wurtzite (hexagonal phase) struc...

The plastic blunting process during stage II fatigue crack growth was studied in pure polycrystalline Ni to investigate effects of strain localization and inelastic behavior on the kinematics of crack advance. Correlations were obtained between strain fields ahead of a fatigue crack, crack advance per cycle and crack growth kinetics. Strain fields were quantified using a combination of in situ ...