Left atrial myxomas are benign tumors are benign tumors that can be life-threatening depending on their location. We report the case of a 70 years old female patient, enrolled in our training program for the management of respiratory distress associated with acute hemodynamic pulmonary edema. Echocardiography objectified mitral valve myxoma associated with left atrial dilation and pulmonary art...

INTRODUCTION Pulmonary hamartoma is a rare benign tumor of the lung, accounting for 3% of all tumors of the lung (1). The term hamartoma was first introduced by Albrecht in 1904 to describe tumor-like malformations resulting from a presumptive development abnormality. In 1934, Goldsworthy applied this term to benign tumors located in the lung that were predominantly composed of a combination of...

Relevance. Pulmonary lesions of infectious etiology in oncohematological children are common and, some cases, may be accompanied by a lethal outcome. When pulmonary tissue on the background hematopoiesis aplasia post-chemotherapy period is shown bronchoscopy to determine genesis identified changes. Aim. To diagnostic value with BAL diseases. Materials and methods. 25 bronchoscopies were perform...

metallothionein (mt) manifests varying expression levels in carcinomas, and they may be considered as valuable cell cancerization biomarkers for diagnosis of patients with cancers. a meta-analysis was conducted to evaluate comprehensively the mt expression difference in various benign tumors and malignant tumors, which compared the high with low mt expression levels in patients of the available...

matous or leiomyomatous, are the most common benign tumors of the lung. However, multiple pulmonary chondromatous hamartomas are rare with less than 20 cases having been previously reported (1). These lesions have also been known to coexist with certain other diseases. The majority of such tumors are small and solitary (2). We present a case of a giant pulmonary chondromatous hamartoma with mul...

Iron overload is known to occur in the West European and American population due to the consumption of iron-rich diets. On the other hand, genetic disorders leading to iron overload are also known. Iron overload leads to increased peroxidation and disruptive disintegration of lipid-rich membranes, and predisposes humans for an enhanced risk of cancer induction. In experimental animals iron ...

Tissue-specific differentiation programs become dysregulated during cancer evolution. The transcription factor Nkx2-1 is a master regulator of pulmonary differentiation that is downregulated in poorly differentiated lung adenocarcinoma. Here we use conditional murine genetics to determine how the identity of lung epithelial cells changes upon loss of their master cell-fate regulator. Nkx2-1 del...

The CA 19.9 antigen is a glycoprotein synthesized in several epithelia that is typically high in the serum of patients with pancreatic tumors. Thus, levels above 300 U/l have a positive predictive value of about 90%.1 Other tumors (bile duct, gastric, colon, hepatic, ovarian, endometrial, pulmonary, or urothelial) or different benign processes (hepatitis, cirrhosis, cholangitis, cholecystitis, ...

Tumor cell survival characteristics were assessed following 60Co gamma-irradiation of the Lewis lung carcinoma as 500-cu mm s.c. tumors or as 0.5-cu mm (1 mm in diameter) pulmonary metastases. Cells in the small pulmonary tumors were markedly more radiosensitive (D0 = 106 rads; hypoxic fraction less than 0.005) than were those in large s.c. tumors (final D0, 315 rads; hypoxic fraction, 0.36). W...

includes radical surgery, radiation and/or drug therapy. In the last decade, regional chemotherapy by perfusion of the pulmonary vascular bed in the treatment of selected patients with pulmonary neoplasms has become a reality (6, 9, 10, 23, 25). Conceivably, this therapy could be come even more effective if the blood supply to developing lung tumors were more thoroughly understood. The human lu...