Tolazoline is a non-selective competitive α-adrenergic receptor antagonist. It is a vasodilator that is used to treat spasms of peripheral blood vessels (as in acrocyanosis).Tolazoline is indicated in the treatment of persistent pulmonary hypertension in the newborn (persistent fetal circulation) when systemic arterial oxygenation cannot be maintained by supplemental oxygen and mechanical venti...

In a rapidly changing environment, national institutions in charge of health security can no longer rely only on traditional disease reporting mechanisms that are not designed to recognise emergence of new hazards. Epidemic intelligence provides a conceptual framework within which countries may adapt their public health surveillance system to meet new challenges. Epidemic intelligence (EI) enco...

Private retrieval of public data is useful when a client wants to query a public data service without revealing the specific query data to the server. Computational Private Information Retrieval (cPIR) is able to achieve complete privacy for a client, but is deemed impractical since it involves expensive computation on all the data on the server. Besides, it is inflexible if the server wants to...

From 1960 to 1990, the Fundação de Serviços de Saúde Pública (Public Health Services Foundation) was in charge of a network of health services across Brazil, in continuation of work previously done by the Serviço Especial de Saúde Pública (Special Public Health Service). The article presents a 2010 research conducted in the state of Amazonas regarding the Foundation's activities among indigenou...

the purpose of this investigation was directed to propose sensitive, accurate and reproducible methods of analysis that can be applied to determine distigmine bromide (dtb), cyclopentolate hydrochloride (cphc), diaveridine hydrochloride (dvhc) and tetrahydrozoline hydrochloride (thhc) drugs in pure form and pharmaceutical preparations via charge-transfer complex formation with 7,7,8,8-tetracyan...

tyrosinase is a multifunctional copper-containing enzyme. it can catalyze two distinct reactions of melanin synthesis and benzaldehyde derivatives, which are potential tyrosinase inhibitors.  to find the relationships between charge distributions of benzaldehyde and their pharmaceutical behavior, the present study aimed at investigating nuclear quadrupole coupling constants of quadrupolare nucl...

objective(s): iscomatrix vaccines have now been shown to induce strong antigen-specific cellular or humoral immune responses to a broad range of antigens of viral, bacterial, parasite or tumor. in the present study, we investigated the role of iscomatrix charge in induction of a th1 type of immune response and protection against leishmania major infection in balb/c mice.  materials and methods:...

the interaction between benzo-15-crown-5 (b15c5), dibenzo-18-crown-6 (db18c6), dibenzyl-daza-18crown-6 (dbzda18c6), n-phenyl-aza-15-crown-5 (npha15c5) and dibenzopyridine-18-crown-6 (dbpy18c6) with π-acceptor 2,3-dichloro-5,6-dicyanobenzoquinone (ddq) in chloroform solution was studied spectrophotometrically. the interaction of b15c5-ddq and db18c6-ddq caused the formation of 1:1 charge transfe...

background: this study assessed the clinical usefulness of the solid phantom, which may compensate for the disadvantages of the water phantom, by comparing the radiological doses between the two depending on their depths. materials and methods: the experimental equipment used was a linear accelerator for medical use, water phantom, solid phantom, farmer type ion chamber and electrometer. the di...