OBJECTIVES To determine whether thyroxine treatment is effective in patients with symptoms of hypothyroidism but with thyroid function tests within the reference range, and to investigate the effect of thyroxine treatment on psychological and physical wellbeing in healthy participants. DESIGN Randomised double blind placebo controlled crossover trial. SETTING Outpatient clinic in a general ...

Objective: Huntington’s disease (HD) is characterized by motor symptoms, psychiatric symptoms and cognitive impairment in, inter alia, executive functions and social cognition. The aim of this study was to investigate the relationship between subjective feeling of psychological distress using a self-report questionnaire and performances on tests of executive functions and social cognition in a ...

The goal of this study was to assess the impact of individual neuropsychological differences on the ability to share attention between concurrent tasks. Participants (n = 20) were trained on six single task practice sessions and dual-task was assessed with reaction time performance on a psychological refractory period (PRP) paradigm. Neuropsychological test scores were also acquired. Furthermor...

During an investigation into the clinical effects of prefrontal leucotomy, an attempt was made to design a simple psychological test procedure sensitive to organic damage to the frontal lobes. The preliminary results obtained with the perceptual maze test reported below suggest that it is sensitive both to cerebral damage in the frontal regions and to damage to the anterior temporal lobe. Becau...

Findings are presented of a comparative study investigating the family relationships and the emotional and gender development of children raised in lesbian mother families. A total of 30 lesbian mother families with 4-8 year old children created as a result of donor insemination (DI) were compared with 38 heterosexual families with a DI child and with 30 heterosexual families who had a naturall...

One of the chronic points of tension between experimental psychologists and clinical psychologists has been on the question of prediction. The experimentalist contends that genuine science leads to prediction, and doubts that the clinician can achieve it. Clinicians who assert that they can make valid forecasts of the behavior of their patients rarely publish materials which prove this can be d...