PURPOSE To investigate the neuronal response to ischemic injury following exposure to whole brain proton irradiation. METHODS Brain only proton irradiation (8 Gy, 250 MeV) was performed ten days prior to middle cerebral artery occlusion (MCAO) in 1 year old male Sprague Dawley rats. MCAO was induced in two animal groups: proton irradiated (MCAO + Rad) and MCAO only. Magnetic resonance imaging...

Ices at ∼15 K consisting of the polycyclic aromatic hydrocarbon coronene (C24H12) condensed either with H2O, CO2, or CO in the ratio of 1 : 100 or greater have been subjected to MeV proton bombardment from a Van de Graaff generator. The resulting reaction products have been examined by infrared transmissionreflection-transmission spectroscopy and by microprobe laser-desorption laser-ionization ...

Proton and ion beams open up new vistas for the curative treatment of tumors, but adequate technologies for monitoring the compliance of dose delivery with treatment plans in real time are still missing. Range assessment, meaning the monitoring of therapy-particle ranges in tissue during dose delivery (treatment), is a continuous challenge considered a key for tapping the full potential of part...

PURPOSE To evaluate the long-term efficacy and outcome of low-dose proton beam irradiation in the treatment of symptomatic circumscribed choroidal hemangioma. PATIENTS AND METHODS Retrospective review of 71 patients with symptomatic circumscribed choroidal hemangiomas treated by proton beam irradiation between September 1994 and October 2002 using a total dose of 20 Cobalt Gray Equivalent. ...

9.1 Background to Proton Therapy The use of proton beams for radiation treatment was proposed by Robert R. Wilson in 1946 [286]. Wilson referred to the ballistical aspects of the proton beam dose distribution as a rationale for the new modality. Heavy charged particles such as protons produce an energy deposition profile in tissue which is superior to profiles attainable using photon or electro...

Introduction Proton-Electron Double-Resonance Imaging (PEDRI) provides a method for in vivo or ex vivo imaging of free radicals in biological tissues and living animals [1]. This technique is based on the Overhauser effect with irradiation and saturation of the electron spin system during the acquisition of a proton magnetic resonance image. An enhancement of the NMR signal of up to two orders ...

Abstract AlGaN/GaN high electron mobility transistors (HEMTs) with different device sizes were prepared and exposed to 0.4 MeV proton irradiation. The low-field carrier transport characteristics of the gate channel are obtained from capacitance-voltage curves current-voltage curves. For a longer gate-drain distance (30 μm), after irradiation, gate-channel increases by 14.3% on average. shorter ...

Perovskite solar cells (PSCs) are studied in low-intensity low-temperature (LILT) conditions before and after low energy proton irradiation to characterize device performance at deep space mission-relevant light intensities temperatures.

-We present the first experimental results of the effects of 63MeV proton irradiation on SiGe HBT analog and RF circuits and passive elements. A SiGe HBT bandgap reference circuit, commonly used to generate stable on-chip voltages in analog IC’s, a SiGe HBT voltage controlled oscillator, an key building block for RF transceivers, and an LC bandpass filter routinely used in RF circuit design, we...