Serum prostate-specific antigen (PSA) levels are used to monitor the development of prostate cancer, recurrence after surgery, and response to subsequent therapy. However, the clinical implications often are difficult to interpret. Ulmert and colleagues report use of a positron-emitting labeled monoclonal antibody directed to a unique PSA epitope to noninvasively image PSA-positive prostate can...

  Introduction: Prostate specific antigen (PSA) is one of the most sensitive markers for diagnosis of prostate cancer. Immunoradiometric kit (IRMA) is a common and sensitive method for determination of PSA in clinical laboratories. This kit has four major components: solid phase coated with monocolonal antibody, pair antibody labelled with I-125, series of standards i...

conclusions our study showed that microrelin is as effective as diphereline in reducing psa and testosterone and can be recommended to initiate medical castration in patients with pc. results each group contained 40 patients. in group a, psa was reduced from 75.78 ± 72.43 ng/ml to 1.93 ± 1.40 ng/ml after 6 months and testosterone was reduced from 3.50 ± 1.12 nmol/l to 0.81 ± 0.05 nmol/l. there ...

INTRODUCTION The objective of this study was to evaluate the value of serum prostate-specific antigen (PSA) and prostate-specific antigen density (PSAD) in the diagnosis of prostate cancer. MATERIALS AND METHODS A total of 330 consecutive patients suspected of having prostate cancer due to either abnormal digital rectal examination or elevated serum PSA levels underwent transrectal ultrasonog...

Prostate cancer is the most common malignant tumor in men. The vast majority of prostate tumors are represented by prostatic adenocarcinomas (up to 95%). Sarcoma a very rare adults with formidable prognosis. Early diagnosis and radical surgery offer patients best chance cure. We report case 44-year-old patient stage VI unresectable high-grade undifferentiated sarcoma, initially presenting urina...

Granulomatous prostatitis is a rare benign inflammatory condition of prostate. It is mistaken for prostatic carcinoma. Clinically it presents as hard nodule on digital rectal examination with raised serum prostate specific antigen (PSA) levels and reduced free PSA levels. We report a rare case of non-specific granulomatous prostatitis clinically diagnosed as carcinoma prostate.

A highly sensitive nested reverse transcriptase-PCR assay, with primers derived from the prostate-specific antigen (PSA) and prostate specific membrane antigen (PSM) cDNA sequences, has been used to detect occult hematogenous micrometastatic prostate cells. In 77 pa tients with prostate cancer, PSM and PSA primers detected circulating prostate cells in 48 (62.3%) and 7 (9.1 %) patients, respect...

The study was conducted on 90 serum samples of people with prostate diseases (G1-include 24 for patients cancer-PC , G2- include benign prostatic hyperplasia-BPH and 22 prostatitis G3), compared 20 healthy individuals as control group. Prostate-specific antigen-PSA, human kallikrein-2-hK2, fibrinogen gamma-FGG, total anti-oxidant capacity-TAC, Vitamin D3-VD3. results showed that the activity PS...

Abstract Prostate cancer screening based on prostate-specific antigen (PSA) testing has been a matter of controversy. Although for prostate was effective in reducing mortality, it resulted overdiagnosis, which translated into unnecessary treatments and numerous adverse effects. As result, recommendations from scientific societies became increasingly restrictive. In the recent years, new approac...

Introduction: As a glycoprotein, Plasma Prostate-Specific Antigen (PSA) is mainly produced by prostate epithelial cells and is used as a major diagnostic tool for prostate cancer. A group of researchers relate the elevated number of estrogen receptors in breast cancer samples to the over-production of PSA in this type of cancer. Therefore, the present study aimed to determine the participants' ...