BACKGROUND We evaluated the cancer detection rate of prostate cancer using transperineal template-guided saturation biopsy aimed at sampling one core for each milliliter of prostate volume for patients requiring repeated prostate biopsies. METHODS In total, 103 consecutive patients with repeated prostate biopsies were enrolled in this retrospective study. The number of biopsy cores was define...

BACKGROUND Transrectal ultrasound (TRUS)-guided prostate biopsies are among the most common outpatient diagnostic procedures in urology clinics and carry the risk of introducing pathogens that may lead to infection. OBJECTIVE To investigate the effectiveness of procedures for disinfecting a probe used in ultrasound-guided prostate biopsy. METHOD The effectiveness of disinfection was determi...

This article is Part 2 of a two-part discussion of prostate cancer from an underwriting perspective that covers clinical staging, tissue staging, and follow-up of treated prostate cancer. Prostate biopsy is the diagnostic gold standard. Needle biopsy technique, sensitivity and specificity, and interpretation of findings, including a detailed discussion of Gleason grading, are discussed. Prostat...

MRI-guided prostate needle biopsy requires compensation for organ motion between target planning and needle placement. Two questions are studied and answered in this work: is rigid registration sufficient in tracking the targets with a maximum error of 3 mm (smaller than average prostate tumor size) and how many intra-operative slices are required to obtain this accuracy? We developed rigid and...

We report a case of prostate cancer in 34 year old man presenting with generalized lymphadenopathy mimicking malignant lymphoma without any urinary symptoms. Lymph node biopsy revealed metastatic adenocarcinoma and immunohistochemical stain was strongly positive to prostate antigen (PSA). Serum PSA level was also markedly elevated. Transrectal ultrasonogram showed mild enlargement in right lobe...

Prostatic massage specimens are not consistent in producing adequate material. Also, the possibility of contamination from other parts of the urinary tract cannot be discounted. It is of no value in latent or occult carcinoma (6, 13, 22), though some authors have been highly successful in the diagnosis of prostatic carcinoma by this method (16). Popular concensus of opinion agrees that 85-950/o...

Figure 2: The robotic system developed for MR image-guided prostate biopsy and brachytherapy. The robot operates inside the bore during imaging, is registered to the scanner using a fiducial frame, and aligns the needle to targets selected in intraoperative MR imaging. The needle is inserted using a master device that lets the clinician stand beside the patient, view real-time MR images aligned...

OBJECTIVES To determine whether antimicrobial prophylaxis could prevent infections after transrectal needle biopsy of the prostate using automated biopsy devices. METHODS We conducted a prospective, randomized, double-blind, multicenter trial in which a total of 537 patients received either oral ciprofloxacin 500 mg or placebo before transrectal needle biopsy of the prostate. Repeated urine c...