Introduction Prostate is one of the treatment sites that is well suited for IMRT. For localized prostate cancer radiation therapy it is one of the effective modalities. However, radiation induced complications such as, urinary incontinence, rectal bleeding are some of the side effects. With traditional treatment techniques such as 4-field box or bi-lateral arc, doses in the range of 60-70Gy can...

Radiotherapy has an important role in the treatment of prostate cancer. Three-dimensional conformal radiation therapy (3D-CRT), intensity modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) techniques are all applied for this purpose. However, the risk of secondary radiation-induced bladder cancer is significantly elevated in irradiated patients compared surgery-only ...

The increased frequency of PSA testing has led to an increased diagnosis of early organ confined prostate cancer. Diagnosis is primarily made by histology, via TRUS-guided sextant biopsy or template biopsy which can provide improved localisation of cancer within the prostate. Staging is from digital rectal examination, from imaging with multi-parametric MRI (TNM staging), from PSA levels, and f...

Radiation therapy has been one of the major treatment modalities for the prostate cancer over the past few decades. Treatment planning system (TPS) is an integral component in radiation therapy in order to ensure the accurate estimation of radiation dose to the tumor. However, due to the variability in optimization techniques and beam modeling among various TPS, the current literature on radiat...

PURPOSE Despite increasing use, proton therapy (PT) remains a relatively limited resource. The purpose of this study was to assess clinical and demographic differences in PT use for prostate cancer compared to intensity modulated radiation therapy (IMRT) at a single institution. METHODS AND MATERIALS All patients with low- and intermediate-risk prostate cancer (N = 633) who underwent definiti...

Background To present the early findings of a phase I clinical trial studying the use of intensity modulated radiation treatment (IMRT) to treat at risk pelvic and lower para-aortic lymph nodes in patients with high risk prostate cancer while escalating dose. Dose escalation was performed with a technique particularly aiming to limit the dose to surrounding critical structures. Methods A tota...

Background: The present work aims to study the out-of-field photon calculation accuracy of a commercial treatment planning system (TPS), Oncentra, for three-dimensional conformal radiotherapy (3D-CRT) and intensity modulated radiation therapy (IMRT) treatment techniques from Elekta Synergy medical linear accelerator. Materials and Methods: Accuracy of individual out-of-field dose components was...

PURPOSE Radiation therapy (RT) is delivered as adjuvant and salvage therapy after radical prostatectomy for prostate cancer. Interest in dose escalation in this setting may necessitate more advanced RT techniques, such as intensity modulation. This study was designed to compare intensity-modulated radiation therapy (IMRT) versus 3-dimensional conformal radiation therapy (3DCRT) planning. METH...

Purpose: To compare target coverage and organ at risk (OAR) sparing in the supine and prone positions with 3-dimensional conformal radiotherapy (3DCRT), intensity-modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT) in lowand high-risk prostate radiotherapy cases. Materials and Methods: Using magnetic resonance images of five healthy volunteers, six treatment plans (supine ...

The purpose of the present study was to assess the results of two different treatment approaches for clinically localized prostate cancer: intensity-modulated radiation therapy (IMRT) followed by 125I seed-implant brachytherapy and 125I seed-implant brachytherapy alone. We studied our 30 most recent consecutive patients. The sample population consisted of 15 cases treated with IMRT (50.4 Gy) fo...