The extracellular calcium-sensing receptor (CaSR) is a G-protein coupled receptor that monitors the systemic extracellular free ionized calcium level ([Ca(2+)]o) in organs involved in systemic [Ca(2+)]o homeostasis. CaSR is widely expressed in the nervous system and its activation promotes axon and dendrite growth during development, but the mechanism by which it does this is not known. Here we...

Adverse reactions of acetaminophen have been associated to oxidative stress, which may be elicited by reactive oxygen species (ROS) and/or production of the metabolite NAPQI. Both phenomena would arise through the activity of liver cytochrome P450 (CYP450) system, but their contribution to this oxidative stress is yet to be clarified. A NADPH oxidase activity has been proposed in rat liver micr...

New bis(N,N-trimethylsilylarylamidinate) zirconium dichloride complexes with various carbon substituents were prepared, and their solid as well as solution state structures were studied. In the polymerization of propylene, after activation by MAO, these catalysts provided two fractions. Ether soluble polymers were obtained at a low activity as sticky polymers with lower molecular weights, excep...

in a novel dual bed reactor fischer-tropsch synthesis was studied by using two diffrent cobalt catalysts. an alkali-promoted cobalt catalyst was used in the first bed of a fixed-bed reactor followed by a rutenuim promoted cobalt catalyst in the second bed. the activity, product selectivity and accelerated deactivation of the system were assessed and compared with a conventional single bed react...

in the present work, the effect of milk supplementation on viability of yogurt bacteria (streptococcus thermophilus and lactobacillus delbrueckii subsp. bulgaricus) and probiotic bacteria (lactobacillus acidophilus and bifidobacteria) was studied during yogurt manufacture and thirty three days storage. incubation time to reach ph value of 4.5 was greatly affected by the addition of casein fract...