objective: the anti-cancer properties of curcumin, a poliphenol extract from the rhizome of curry, has been confirmed by many investigators. however, low levels of uptake, tissue distribution and rapid metabolism has limited its application as an anti-cancer drug. this study is aimed at increasing curcumin's water solubility due to a biodegradable, neutral and non-toxic micellar nano-carrier ca...

The control of tokamak fusion experiments is outlined with particular reference to the evolution of the control from primitive pre-programmed operation, through to feedback control of many parameters, finally developing advanced methods which are destined to optimise the performance of the tokamak plasma. Four examples of enhanced control of tokamak plasmas are given.

Studies of developmental cell death in the nervous system have revealed two different modes of programmed cell death (PCD). One results from competition for target-derived trophic factors and leads to the stochastic removal of neurons and/or glia. A second, hard-wired form of PCD involves the lineage-specific, stereotypical death of identifiable neurons, glia or undifferentiated cells. Although...

An autonomous control system designed for a non-holonomic wheeled mobile robot that is programmed to emulate a fixed-wing unmanned air vehicle (UAV) flying at constant altitude is experimentally validated. The overall system is capable of waypoint navigation, threat avoidance, real-time trajectory generation and trajectory tracking. Both the wheeled mobile robot experimental platform and the hi...

programmed cell death, which can be classified into apoptosis, autophagy, and oncosis, based on the cellular signalling pathways involved in the process, plays a critical role in cellular house-keeping. aberrant cell death regulation leads to body malformations, as well as to numerous diseases. here, we describe the effects of cytototoxins isolated from marine organisms on the various programme...

We propose a new theory to explain developmental aberrations in plant hybrids. In our theory, hybrid incompatibilities arise from imbalances in the mechanisms that cause male sterility in hermaphroditic plants. Mitochondria often cause male sterility by killing the tapetal tissue that nurtures pollen mother cells. Recent evidence suggests that mitochondria destroy the tapetum by triggering stan...