نتایج جستجو برای: prognostic

تعداد نتایج: 111146  

2012
Timothy J. Molloy Paul Roepman Bjørn Naume Laura J. van't Veer

The detection of circulating tumor cells (CTCs) in the peripheral blood and microarray gene expression profiling of the primary tumor are two promising new technologies able to provide valuable prognostic data for patients with breast cancer. Meta-analyses of several established prognostic breast cancer gene expression profiles in large patient cohorts have demonstrated that despite sharing few...

2017
Jian-Yong Wang Ling-Ling Chen Xiong-Hui Zhou

Identifying the prognostic genes in cancer is essential not only for the treatment of cancer patients, but also for drug discovery. However, it's still a big challenge to select the prognostic genes that can distinguish the risk of cancer patients across various data sets because of tumor heterogeneity. In this situation, the selected genes whose expression levels are statistically related to p...

2017
Hongwei Li Weili Wang Haixia Jia Jianhong Lian Jianzhong Cao Xiaqin Zhang Xing Song Sufang Jia Zhengran Li Xing Cao Wei Zhou Songye Han Weihua Yang Yanfen Xi Shenming Lian

BACKGROUND Several indices have been developed to predict survival of brain metastases (BM) based on prognostic factors. However, such models were designed for general brain metastases from different kinds of cancers, and prognostic factors vary between cancers and histological subtypes. Recently, studies have indicated that epidermal growth factor receptor (EGFR) mutation status may be a poten...

Journal: :razavi international journal of medicine 0
narges jafarzadeh department of research and education, razavi hospital, mashhad, ir iran hami ashraf department of research and education, razavi hospital, mashhad, ir iran; zakaria idea and innovation support and leading center, tehran, ir iran fahimeh khoshroo department of research and education, razavi hospital, mashhad, ir iran alireza sepehri shamloo student research committee, mashhad university of medical sciences, mashhad, ir iran farzad bidouei department of research and education, razavi hospital, mashhad, ir iran kamran ghaffarzadehgan department of research and education, razavi hospital, mashhad, ir iran; department of research and education, razavi hospital, mashhad, ir iran. tel: +98-5116004594, fax: +98-5116668883

context triple negative breast cancer (tnbc) is a heterogeneous group of diseases that is negative for esterogen receptor (er) progesteron receptor (pr) and human epidermal growth factor receptor 2 (her2). this type of breast cancer is typically high-grade carcinomas, although low-grade tumors occur. the aim of this review is to focus on molecular classification and features, prognostic markers...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2016
Shuang G Zhao Joseph R Evans Vishal Kothari Grace Sun Ashley Larm Victor Mondine Edward M Schaeffer Ashley E Ross Eric A Klein Robert B Den Adam P Dicker R Jeffrey Karnes Nicholas Erho Paul L Nguyen Elai Davicioni Felix Y Feng

PURPOSE There is a clear need to improve risk stratification and to identify novel therapeutic targets in aggressive prostate cancer. The goal of this study was to investigate genes with outlier expression with prognostic association in high-risk prostate cancer patients as potential biomarkers and drug targets. EXPERIMENTAL DESIGN We interrogated microarray gene expression data from prostate...

In addition to histopathological parameters, evaluation of associated hematological factors is essential for devising a sensitive prognostic scale in glioma. Increased neutrophil-lymphocyte ratio (NLR), a marker of systemic inflammatory response, has recently been associated with worse outcome in various cancers. Given that glioma progression is characterized by inflammation, aggressive angioge...

A. Khajehdehi GR. Rezaian P. Khajehdehi Sh. Beheshti,

Background: The predisposing and prognostic factors for neonatal tetanus (NNT) have not been adequately studied in southernIran. Objective: The present study was undertaken in Fars Province to further clarify the status of neonatal tetanus in this region. Methods: The mortality rate was correlated with demographic and clinical findings in 112 cases of neonatal tetanus.  In addition, the height ...

Journal: :Anticancer research 2012
Manabu Morimoto Kazushi Numata Satoshi Moriya Masaaki Kondo Akito Nozaki Yu Morioka Shin Maeda Katsuaki Tanaka

BACKGROUND No reliable prognostic predictor is known for patients undergoing sorafenib treatment for advanced hepatocellular carcinoma (HCC). PATIENTS AND METHODS In 81 patients receiving sorafenib treatment for advanced HCC, we evaluated the prognostic significance of an inflammation-based prognostic score, the Glasgow prognostic score [evidenced by an elevated C-reactive protein level (>1.0...

2014
Yang Yang Leng Han Yuan Yuan Jun Li Nainan Hei Han Liang

Prognostic genes are key molecules informative for cancer prognosis and treatment. Previous studies have focused on the properties of individual prognostic genes, but have lacked a global view of their system-level properties. Here we examined their properties in gene co-expression networks for four cancer types using data from 'The Cancer Genome Atlas'. We found that prognostic mRNA genes tend...

Journal: :caspian journal of internal medicine 0
behzad heidari

chronic obstructive pulmonary disease (copd) is a condition associated with inflammation in lungs and airways. the impacts of inflammatory process is not limited to respiratory system but extend to extrapulmonary organs with resultant complications involving endocrine, metabolic and cardiovascular systems. the extent and severity of inflammation may be partly estimated by serum measurement of s...

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