Hansen, T. V. A., Fryganas, C., Acevedo, N., Carballo, L. R., Thamsborg, S. M., Mueller-Harvey, I. and Williams, A. R. (2016) Proanthocyanidins inhibit Ascaris suum glutathione-Stransferase activity and increase susceptibility of larvae to levamisole and ivermectin in vitro. Parasitology International, 65 (4). pp. 336-339. ISSN 1873-0329 doi: 10.1016/j.parint.2016.04.001 Available at http://cen...

Grape pomaces or vinification by-products are abundant and rich in polyphenols, particularly proanthocyanidins. During the last three decades, grape wine catechins (CATs) oligomeric proanthocyanidins (OPCs) have attracted considerable attention of international scientific community, due essentially to their potential health-beneficial effects, related protective action towards cardiovascular di...

The aim of the present study was to examine the protective effect of proanthocyanidins anoxia-reoxygenation injury of myocardial cells and its association with phosphatidylinositol-3-kinase/Akt and glycogen synthase kinase (PI3K/Akt/GSK)-3β and ATP-sensitive potassium channels. Neonatal rat myocardial cells were cultured and an anoxia-reoxygenation model was established following pretreatment w...

BACKGROUND The aerial parts of Rumex acetosa L. have been used in traditional European medicine for inflammatory diseases of the mouth epithelial tissue. The following study aimed to investigate the influence of a proanthocyanidin-enriched extract from R. acetosa extract against the adhesion of Porphyromonas gingivalis (P. gingivalis), a pathogen strongly involved in chronic and aggressive peri...

Learning and memory abilities are associated with alterations in gut function. The two-way proanthocyanidins-microbiota interaction in vivo enhances the physiological activities of proanthocyanidins and promotes the regulation of gut function. Proanthocyanidins extracted from lotus seedpod (LSPC) have shown the memory-enhancing ability. However, there has been no literature about whether Lactob...

The pathogenesis of periodontitis involves anaerobic oral bacteria as well as the host response to infection and several drugs have been developed which can curtail these deleterious effects. Proanthocyanidin, a novel flavanoid extracted from grape seeds, has been shown to provide a significant therapeutic effect on endotoxin (Escherichia coli) induced experimental periodontitis in rats. In thi...