objective(s) production of extended-spectrum beta-lactamases (esbls) by enteric bacteria continues to be a major problem in hospitals and community. esbls producing bacteria cause many serious infections including urinary tract infections, peritonitis, cholangitis and intra-abdominal abscess. the aim of this study was to determine the prevalence of esbls producing escherichia coli and klebsiell...

background: radiation therapy is among the most conventional cancer therapeutic modalities with effective local tumor control. however, due to the development of radio-resistance, tumor recurrence and metastasis often occur following radiation therapy. in recent years, combination of radiotherapy and gene therapy has been suggested to overcome this problem. the aim of the current study was to e...

genome-wide association studies (gwas) have identified genetic variants contributing to the risk of cardiovascular disease (cvd) at the chromosome 9p21 locus. the chromosome 9p21 is an important susceptibility locus for several multifactorial diseases like ischemic stroke, aortic aneurysm, type 2 diabetes mellitus and coronary artery disease (cad). f7 gene because of its role in activating the ...

introduction: endometriosis is a prevalent gynecological disorder among women which is diagnosed by the growth of endometrial tissue outside of uterus and is mainly accompanied by severe pelvic pain and infertility. p53 also known as cellular tumor antigen p53 inside codons 11, 72 and 248 are contained with single nucleotide changes in which tends to be nearly rampant.this will probably be incr...

results slow and fast-growing groups of the mycobacterium strains were clearly differentiated based on the constructed tree of 56 common mycobacterium isolates. each species with a unique title in the tree was identified; in total, 13 nods with a bootstrap value of over 50% were supported. among the slow-growing group was mycobacterium kansasii, with m. tuberculosis in a cluster with a bootstra...

background: histones are replaced by protamines to condensate and package dna into the sperm head during mammalian spermatogenesis. protamine genes defects have been reported to cause sperm dna damage and male infertility. objective: in this study relationship among some protamines genes family snps include prm1 (c321a), prm2 (c248t) and tnp2 (t1019c), (g1272c), (g del in 1036 and 1046 bp) were...

no abstract is provided.

introduction: cryptorchidism has been proved to cause apoptosis in germ cells in respond to changes in the stimulation levels of specific physiological events. the purpose of this study was to determine whether treatment of bilateral cryptorchidism was associated with alterations in testicular gene expression. methods: to induce bilateral cryptorchid model, immature mice were anesthetized and a...

idiopathic chronic urticaria (icu), the most common form (70-80%) of chronic urticaria is supposed to have immune basis causes. it is speculated that the promoter polymorphism of tgf-β1 gene may be involved in icu. this condition is thought to affect at least 0.1% of the population and often can be severe and difficult to treat. a total of 40 patients with icu and 41 normal subjects were studie...