Kidney collecting duct principal cells play a key role in regulated tubular reabsorption of water and sodium and secretion of potassium. The importance of this function for the maintenance of the osmotic homeostasis of the whole organism motivates extensive study of the ion transport properties of collecting duct principal cells. We performed experimental measurements of cell volume and intrace...

in this paper two nodes to model isotropic and anisotropic media in transmission line matrix method (tlm) are presented. by using these two nodes, the permeability and permittivity of an anisotropic media can be modeled simultaneously. another application of these nodes is in modeling media with permittivity and permeability less than one. in the conventional 2 dimensional tlm, the stubs repres...

Vasopressin, a neurohypophyseal peptide hormone, is the endogenous agonist at V1a, V1b, and V2 receptors. The most important physiological function of vasopressin is the maintenance of water homeostasis through interaction with V2 receptors in the kidney. Vasopressin binds to V2 receptor and increases the number of aquaporin-2 at the apical plasma membrane of collecting duct principal cells. Th...

Induction heating of cylindrical nonmagnetic billets by their rotation in static magnetic field is modeled. The magnetic field is produced by a system of appropriately arranged permanent magnets. The numerical model is solved by our own full adaptive higher-order finite element method in a monolithic formulation, i.e., both magnetic and temperature fields are solved simultaneously, respecting t...

Permeability can be directly measured using cores taken from the reservoir in the laboratory. Due to high cost associated with coring, cores are available in a limited number of wells in a field. Many empirical models, statistical methods, and intelligent techniques were suggested to predict permeability in un-cored wells from easy-to-obtain and frequent data such as wireline logs. The main obj...

Retention behaviour of molecules mostly depends on their chemical structure. Retention data of biologically active molecules could be an indirect relationship between their structure and biological or pharmacological activity, since the molecular structure affects their behaviour in all pharmacokinetic stages. In the present paper, retention parameters (R M (0)) of biologically active 1,2-O-iso...

Differential diagnosis of acute viral hepatitis, persistent chronic hepatitis, aggressive chronic hepatitis, and post-necrotic cirrhosis can reasonably be achieved on the basis of three well-known liver-function tests: aspartate aminotransferase, alanine aminotransferase, and glutamate dehydrogenase. With use of principal-component analysis, these four liver diseases can be characterized by two...

in this study, medium density fiberboard (mdf), was produced by dry process using refined fibers from choob khazare caspian amol factory, with 3 levels of urea formaldehyde adhesive at 8, 10, and 12 percent, and 3 levels of paraffin at 0.5, 1, and 1.5 percent. from every treatment, cylindrical samples for permeability measurement with 13 mm in diameter, and 30 mm of height were cut using hole-s...

Determining permeability of a given compound through human skin is a principal challenge owing to the highly complex nature of dermal tissue. We describe the application of an ambient mass spectrometry imaging method for visualizing skin penetration of sodium channel modulators, including novel synthetic analogs of natural neurotoxic alkaloids, topically applied ex vivo to human skin. Our simpl...