BACKGROUND Previous studies of intrauterine devices (IUDs), many of which are no longer in use, suggested that they might cause tubal infertility. The concern that IUDs that contain copper--currently the most commonly used type--may increase the risk of infertility in nulligravid women has limited the use of this highly effective method of birth control. METHODS We conducted a case-control st...

OBJECTIVE To compare treatment and protection against falciparum malaria in pregnant and non-pregnant women with three drug regimens. DESIGN Prospective intervention study with six weeks' follow up. Patients received one of three drug regimens in order of entry. SETTING Primary care hospital and secondary girls' school in rural western Kenya. PATIENTS 158 of 988 pregnant women (89 primigr...

BACKGROUND Malaria in pregnancy remains a major public health problem especially in sub-Saharan Africa. However, the prevalence of clinical and asymptomatic infection among antenatal client (ANC) attendees is largely unknown, especially at primary health care (PHC) level in northern Nigeria. This study assessed the prevalence of fever, malarial parasitemia and anemia among pregnant women attend...

BACKGROUND It is unknown whether the presence of Plasmodium falciparum malaria parasites in umbilical cord blood denotes infection acquired antenatally or contamination with infected maternal blood at delivery. METHODS Parasites were quantified by real-time quantitative polymerase chain reaction (RTQ-PCR) and were genotyped in paired maternal- and cord-blood samples obtained from 632 pregnant...

BACKGROUND The potential benefit in preventing pelvic floor disorders (PFDs) is a frequently cited reason for requesting or performing cesarean delivery on maternal request (CDMR). However, for primigravid women without medical/obstetric indications, the lifetime cost-effectiveness of CDMR remains unknown, particularly with regard to lifelong pelvic floor consequences. Our objective was to asse...

Torsion of a pedunculated subserous leiomyoma in pregnant woman is rare condition that requires prompt diagnosis and urgent surgical intervention. In this report, we present case torsion primigravid aged 33 years her 30th week gestation. A presented to our clinic gestation with pain the right lower quadrant had developed last 24 hours. Our was leiomyoma. The patient received tocolytic nifedipin...

KEY POINTS Older pregnant women have a greater risk of operative delivery, still birth and post-term induction. This suggests that maternal age can influence the timing of birth and processes of parturition. We have found that increasing maternal age in C57BL/6J mice is associated with prolongation of gestation and length of labour. Older pregnant mice also had delayed progesterone withdrawal a...