نتایج جستجو برای: primary immunodeficiency disease
تعداد نتایج: 2088150 فیلتر نتایج به سال:
In high-burden countries, Mycobacterium bovis Bacillus Calmette-Guérin (BCG) vaccine is administered in newborn to prevent severe Mycobacterium tuberculosis infection. Because life-threatening disseminated BCG disease may occur in children with primary immunodeficiency, vaccination strategy against tuberculosis should be redefined in non-high-burden countries. We report the case of a patient wi...
Levels of Kappa-deleting recombination excision circles (KRECs), T-cell receptor excision circles (TRECs), and T-cell repertoire diversity were evaluated in 1038 samples of 124 children with primary immunodeficiency, of whom 102 (54 with severe combined immunodeficiency and 48 with other types of immunodeficiency) underwent hematopoietic stem cell transplantation. Twenty-two not transplanted pa...
Background: Common Variable Immunodeficiency (CVID) is a primary immunodeficiency disease, characterized by hypogammaglobulinemia and heterogeneous clinical manifestations. This study was performed to evaluate the clinical and immunological features of pediatric patients with CVID. Methods: We reviewed the records of 69 children diagnosed under age of 16 years with CVID (35 males and 34 ...
Immunodeficiency is a common thought among both patients and physicians when confronted with what is perceived as an excessive number, duration, or severity of infections. Because of this, the starting point for evaluating patients for suspected immunodeficiency is based on what constitutes ”too many infections.” It generally is agreed that children with normal immune systems may have an averag...
BACKGROUND Primary antibody deficiency, the most common primary immunodeficiency disorder, represents a heterogeneous spectrum of conditions caused by a defect in any critical stage of B cell development and is characterized by impaired production of normal amounts of antigen-specific antibodies. OBJECTIVE This retrospective study aimed at description and analysis of demographic, clinical, im...
Background: Primary (PID) or secondary (SID) immunodeficiencies are diseases caused by quantitative and/or functional alterations of the different mechanisms involved in innate and adaptive immune response. This economic evaluation was conducted to compare cost treatment HYQVIA® (hyaluronidase-facilitated subcutaneous infusion immunoglobulin, fSCIG) compared intravenous immunoglobulin (IVIG) (S...
More than 20 North American academic centers account for the majority of hematopoietic stem cell transplantation (HCT) procedures for primary immunodeficiency diseases (PIDs), with smaller numbers performed at additional sites. Given the importance of a timely diagnosis of these rare diseases and the diversity of practice sites, there is a need for guidance as to best practices in management of...
Syphilis is considered one of the greatest imitators which can mimic any skin disease. Keen examination together with a sound brain and high degree suspicion required for its diagnosis. Syphilis, sexually transmitted disease caused by spirochete Treponema pallidum pallidum, was more common during Second World War. Later, as human immunodeficiency virus cases increased, there increased,incidence...
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