نتایج جستجو برای: primary cutaneous lymphomas pcls
تعداد نتایج: 702282 فیلتر نتایج به سال:
A high percentage of extracutaneous CD30+ anaplastic large cell lymphomas (nodal ALCL) carry a specific chromosomal translocation, t(2;5) (p23;q35), that results in abnormal expression of p80 NPM/ALK chimeric protein (p80). The protein p80 may be detected by immunohistochemistry using polyclonal (anti-p80) or monoclonal (ALK1) antibody directed against the ALK epitope. Although nodal ALCL, prim...
Cutaneous T-cell lymphomas most commonly have a CD4(+) memory T-cell phenotype with relatively indolent course, but may in rare cases present with a CD8(+) cytotoxic phenotype exhibiting strikingly more aggressive clinical behavior. We present two cases of the clinically aggressive subtype of primary cutaneous epidermotropic CD8(+) cutaneous T-cell lymphoma and review the current literature, cl...
INTRODUCTION Cytotoxic CD8+ T-cell lymphomas are only rarely encountered and thus remain only poorly characterized. Our aim was to collect and correlate clinical and histological data of CD8+ skin lymphoma infiltrates to obtain a proper subtype assignment of CD8+ skin lymphoma infiltrates and to derive putative prognostic markers thereof. METHODS Formalin-fixed and paraffin-embedded (FFPE) ti...
OBJECTIVES To describe clinicopathologic features and to identify prognostic factors in a large series of primary cutaneous diffuse large B-cell lymphoma, leg type (PCLBCL LT), as defined in the recent World Health Organization-European Organization for Research and Treatment of Cancer classification of cutaneous lymphomas. DESIGN Retrospective multicenter study from the French Study Group on...
Cutaneous Lymphomas (CL) are a distinctive group of lymphomas; they are the second most frequent extra nodal lymphomas. They can be defined as lymphoproliferative skin infiltrates of T-, Bor NKcell lineage which typically occur in and remain confined to the skin without detectable extracutaneous manifestation 1. The Cutaneous T-cell Lymphoma (CTCL) spectrum is composed of Mycosis Fungoides (MF)...
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