1970s, ‘The Morning After’ was the title of the daily newspaper of the Sixtieth Annual Conference of the Planned Parenthood Federation of America held in New York.1 Attending the conference during transatlantic study leave, the Honorary Secretary of the National Association of Family Planning Doctors was impressed during the reception at the ‘Windows on the World’ restaurant atop the World Trad...

What is EllaOne? EllaOne contains 30 mg ulipristal acetate (UPA), a synthetic selective progesterone receptor modulator, which has antagonistic and partial agonistic effects at the progesterone receptor level. Consequently, UPA should prevent the gene transcription normally activated by progesterone to produce the necessary proteins to support pregnancy. Over the last 10 years, other progestero...

The postcoital antifertility activity of a series of triarylalkenes and triarylalkanols with basic ether groups has been examined in mice and rats. The triarylalkenes were, in general, more potent than the others, and more potent orally than by injection. Apart from having a greater sensitivity than the mouse, the rat appears to give essentially the same information about relative potency and o...