the histopathological findings include as following: gliosis (52%), neuronal necrosis (37%), perivascular cuffing (5.4%), hyperemia and hemorrhage in cerebral tissues (32.9%), hyperemia and hemorrhage in meninge(19.2%), prevascullar and preneuronal edema (52%), meningial edema (16.4%), vacuole in neurons (2.7%), vacuoleinneuropil( 8.2% ),protozoal cyct(5.4%). frequency of fetal brain lesions co...

In October 2011, an Indian man resident in Italy was admitted to a hospital in Mantua, Italy with symptoms of acute encephalitis. Due to a recent history of bite by a suspected rabid dog in India, where he had received incomplete post-exposure treatment, rabies was suspected. The patient died after 22 days of intensive care treatment and rabies was confirmed post mortem. This report stresses th...

The role of type 2 T cell responses on the severity of post-infectious encephalitis was investigated in a mouse model of influenza virus infection. When mice were infected intracerebrally with 3.0 LD(50) of A/NWS33 strain of influenza virus, they all showed clinical signs of encephalitis, and 90% of them died within 10 days of the infection. However, the post-infectious encephalitis was not dem...

Kid kidney cells form less than 2 months of age were grown, 80% confluent monolayers were obtained after 10-12 days. Live attenuated goat pox virus vaccine (Gorgan 55, Iranian) was used to infect the confluent monolayers. Eighty percent cytopethic effect (CPE) was obtained on day 5 of virus inoculation. TCID50 calculated for the pool virus was 10 / ml. Vaccine was found free from any bacterial ...

Foot-and-mouth disease virus (FMDV) exists as multiple serotypes and strains that infect a range of cloven-hoofed animals with variable severity. Clinical diagnosis reinforced by diagnostic tests support timely intervention, whilst virus characterisation helps trace routes of spread and select appropriate vaccine strains. To speed up and simplify diagnosis, penside tests have recently been deve...

Investigations at Pirbright have shown that strains of virus which a re attenuated and immunogenic for cattle were also attenuated for sheep and produced a good immune response (Report, 1964). The work of Geering & Pay (1963) included studies with the RV11 vaccine strain, which at a high dosage level caused no post vaccinal reactions in a group of twenty four-month old lambs. Examination of the...

Bacillus anthracis can infect both livestock and humans. The importance of the treatment of the disease in humans has been underscored by the bioterrorism events of 2001 in the United States. The presence of PA and B/C genes (pX01 and pX02 plasmids) as well as susceptibility to several antimicrobial substances was determined in 11 strains of Bacillus anthracis isolated during two recent epizoot...

A study to determine the possible role of Japanese encephalitis in the Nipah encephalitis outbreak among pig-farm workers in Malaysia in 1998/1999 was done. Two hundred and twelve patients who fulfilled the criteria of Nipah encephalitis from three epicentres during the outbreak were retrospectively analysed. Twenty-nine of these patients (14%) had positive IgM serology for Japanese encephaliti...