BACKGROUND AND PURPOSE Mitogen-activated protein kinase (MAPK) may be associated with the pathogenesis of cerebral vasospasm after subarachnoid hemorrhage (SAH). This study aimed to clarify the role of MAPK expression and activation during cerebral vasospasm and to evaluate the therapeutic effect on cerebral vasospasm using an antisense MAPK oligodeoxynucleotide (ODN). METHODS Antisense MAPK,...

Non-traumatic dural arteriovenous fistula/malformation (dural AVF/AVM) presenting with pure subdural hematoma (SDH) is relatively rare. We report on a male patient who showed pure acute SDH and was diagnosed as having dural AVF on the convexity near the superior sagittal sinus (SSS), based on angiographic findings. A 27-year-old man was admitted to our hospital due to headache with acute onset....

objective: exposure to traumatic stressors lead to activation of arousal responses mediated by serotonergic and noradrenergic systems and it may cause a change in numerous neurotransmitters and neuroendocrine systems. there is ample experimental and clinical evidence to suggest that ginkgo biloba extract is neuroprotective and has antioxidant properties and can restore stress-induced elevation ...

background: despite the fact that being exposed to traumatic and stressful events could have severe consequences, studies have shown that even in the wake of negative events such as cancer diagnosis, we see some changes and positive impacts in scheme, philosophy of life and self-perception, a process which is called post traumatic growth (ptg). the aim of the current research is to define share...

perhaps, due to the impact of post-traumatic stress disorder (ptsd) on biological markers of cardiovascular such as systolic and diastolic blood pressure, heart rate, body temperature, physiological response to reminders of trauma has become an essential part and hallmark of the diagnostic and statistical manual of mental disorders (fifth edition-dsm-5, american psychiatric association, 2013). ...

background and aim: post-traumatic stress disorder is one of the anxiety disorders which occur in postpartum period. the prevalence of ptsd – induced by preeclampsia has been already reported as 28%, however no study was found to compare ptsd in primiparous and multiparous women. this study was therefore conducted to compare ptsd in primiparous and multiparous women. methods: this comparative d...

results analysis showed that there were no significant differences between the groups at baseline (p < 0.05). comparison of the results between the two groups before the two-step test showed that anger and vitality scales between the two groups have no significant differences, but on the other scales (depression, dizziness, fatigue and tension), differences between pre and post-test groups were...

Non-traumatic subarachnoid hemorrhage (SAH) affects an estimated 30,000 people each year in the United States, with an overall mortality of ~30%. Most cases of SAH result from a ruptured intracranial aneurysm, require long hospital stays, and result in significant disability and high fatality. Early brain injury (EBI) and delayed cerebral vasospasm (CV) have been implicated as leading causes of...

SAH affects 6-9 people per 100,000 of the population per year and constitutes about 6% of first strokes. An apparent decrease from older published figures is attributed to a higher rate of CT scanning, excluding other haemorrhagic causes. Approximately 85% of patients bleed from intracranial arterial aneurysms, 10% from a non-aneurysmal peri-mesencephalic haemorrhage and 5% from other vascular ...

war is an effective factor in incidence and promotion of psychological and behavioral problems such as post-traumatic stress disorder. this study aimed to determine the quality of life and its correlation with age and percent of injury in war veterans with post-traumatic stress disorder. this was a cross-sectional study, which included 70 war veterans with post-traumatic stress disorder. this s...