CuPt/Ag trimetallic alloy nanoparticles (NPs) were synthesized by co-sputtering onto liquid polyethylene glycol (PEG), using a CuPt target and an Ag target.

One of the major obstacles in the development of ligand-targeted liposomes is poor liposome circulation longevity as a result of antibody-mediated elimination of these highly immunogenic carriers. Because studies from our laboratory suggest that it is not possible to reduce the immunogenicity of ligand-conjugated liposomes by using surface-grafted poly(ethylene glycol) (PEG), we investigated th...

Membranes have been developed by coating a blend of chitosan (CS) and polyethylene glycol (PEG) of different molecular weights (4000, 10,000 and 20,000) on cotton fabric followed by freeze drying. The influence of PEG molecular weight on the physical characteristics of the membranes has been investigated. The scanning electron microscopy of the coated fabric reveals porous structure. The porosi...

In this study, we try to answer a fundamental question: what is the consequence of the noncovalent interaction between a polymer and a coordination compound? Here, polyethylene glycol (PEG-4000, PEG-b) and copper complex of ethylenediaminetetraacetic acid (H(2)CuY) were employed to solve this problem. A novel adduct (CEP) between H(2)CuY and PEG-b was prepared. Our results indicated several int...

Non-steroidal anti-inflammatory drugs have an important impact in the actual medicinal therapy, having indications in covering the range from rheumatic inflammations to cardio-vascular, genito-urinary and stomatological diseases. Flufenamic acid is a nonsteroidal anti-inflammatory drug, from the class of fenamates. It exhibits poor aqueous solubility, accordingly the aim of this study was to en...

Affinity-based cell separation is label-free and highly specific, but it is difficult to efficiently and gently release affinity-captured cells due to the multivalent nature of cell-material interactions. To address this challenge, we have developed a platform composed of a capture substrate and a cell-releasing molecular trigger. The capture substrate is functionalized with a cell-capture anti...

The self-assembly in aqueous solution of benzene-1,3,5-tricarboxamide (BTA) bearing one alkyl chain and two PEG (polyethylene glycol) chains or yields molecular-packing driven nanostructures.

Detachment of the cotton fiber cell from the ovule results in loss of over 90% of the in vivo capacity for synthesis of [(14)C]cellulose from [(14)C]glucose. However, over 50% of the capacity for cellulose synthesis in the detached fiber population is protected when polyethylene glycol 4000 is present during detachment and incubation. Radioautography shows that approximately full capacity is re...

Nano-sized γ-Al2O3 was synthesized successfully by a simple method using Al2(SO4)3·18H2O as aluminium source and in the presence of polyethylene glycol (PEG 2000). FTIR spectroscopy, X-ray diffraction (XRD), scanning electron microscope (SEM) and transmission electron microscope (TEM) were used to characterize the structure and morphology of synthesized powder. The results showed that PEG playe...

The present studies were undertaken to develop solvent-free solid dispersions (SDs) for poorly soluble anti-inflammatory drugs mefenamic acid (MA) and flufenamic acid (FFA) in order to enhance their in vitro dissolution rate and in vivo anti-inflammatory effects. The SDs of MA and FFA were prepared using microwaves irradiation (MW) technique. Different carriers such as Pluronic F127® (PL), Eudr...