1 Diamanti-Kandarakis E, Papavassiliou AG. Molecular mechanisms of insulin resistance in polycystic ovary syndrome. Trends Mol Med 2006; 12: 324-332. 2 Azziz R, Carmina E, Dewailly D, et al. Criteria for defining polycystic ovary syndrome as a predominantly hyperandrogenic syndrome: an Androgen Excess Society Guideline. J Clin Endocrinol Metab 2006; 91: 4237-4245. 3 Teede H, Zoungas S, Hutchiso...

Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women of reproductive age, and it is a multifactorial polygenic disorder with a broad spectrum of clinical manifestations. Although pathogenesis is still unclear, androgen receptor (AR) gene polymorphism may be one of the etiologic factors of PCOS. AR gene polymorphism has been also associated with other forms of ...

The objective of this study is to explore how hyperinsulinemia and insulin resistance relate the clinical, endocrine metabolic factors in infertile women with polycystic ovary syndrome. This was conducted on 121 consecutive syndrome attending Infertility unit from January 2017 December 2017. They were divided into two groups: resistant sensitive. There significant difference body mass index wai...

Background: Genetic polymorphism is responsible for variations and individual differences. Polymorphism is a major factor of complex diseases with unknown etiology and cancer. Inconsistency in the symptoms of polycystic ovary syndrome (monthly disorder, hirsutism, obesity, diabetes, infertility) is one of the major pathological complications of this syndrome. The present study was conducted to ...

Background: Polycystic ovary syndrome (PCOs) is an endocrine-metabolic disorder. This study intends to determine the comparison of insulin resistance (IR) and metabolic disturbance in overweight/obese and normal-weight of young women with polycystic ovary syndrome. Methods: Using a comparative cross-sectional study design in 2015, 27 normal weight (18<bmi Results: 112 women with PCOS participa...

Background Polycystic ovary syndrome is a frequent condition in women of reproductive age with prevalence rate of 5-10%. This study purposed to determine the relationship between polycystic ovary syndrome and the outcome of assisted reproductive treatment (ART) cycle in Tehran, Iran. MaterialsAndMethods In this historical cohort study, 996 infertile women who were referred to Royan Institute (T...

Polycystic ovary syndrome is an accumulation of endocrine changes that associates oligo-amenorrhea, obesity, hirsutism, androgen excess and resistance to insulin. Ovarian drilling can be done through classical laparoscopy and by transvaginal hydrolaparoscopy minimally invasive surgical method. We performed a meta-analysis of eight studies conducted between 2003-2011, which include a total of 35...

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Background: Polycystic ovary syndrome (PCOS) is a common endocrine disorder in young women which has different clinical consequences. This study was conducted to evaluate the outcome of long or extended letrozole therapy for induction of ovulation in patients with polycystic ovary syndrome (PCOS). Materials and Methods: This prospective controlled study was conducted in a university hospital on...