Two commercial polychlorinated biphenyl mixtures (Aroclor 1254 and Aroclor 1242) and one polybrominated biphenyl mixture (FireMaster BP-6) were examined for their abilities to induce hepatic microsomal monooxygenation in rainbow trout (Salmo gairdneri). Pretreatment of rainbow trout with Aroclors 1254 and 1242 (150 mg/kg IP) resulted in an approximate 10-fold induction of arylhydrocarbon (benzo...

There are several basic principles that apply to the clinicopathologic syndrome produced by polychlorinated biphenyls (PCBs). They are as follows: The degree of halogenation and position of the halogen atoms determine the potency of PCB, PBB, CDD, CDF and CN; in a given species of animals, the clinicopathologic syndrome induced by PCB is comparable to that induced by polybrominated biphenyls (P...

Background: Polybrominated Biphenyls (PBBs) and Polybrominated Diphenyl Ethers (PBDEs) are semi-permanent Halogenated compounds that are mainly used in flame retardant. These contaminants as endocrinedisrupting associated with dysfunction of immune, endocrine and nervous systems. Influence various physiological processes such as menarche, birth weight, fetus growth and development, head circumf...

Introduction Lake Mjøsa is the largest lake in Norway, with a surface area of 365 km. High levels of some contaminants in fish from the lake have caused public attention and concerns, and health authorities recommend that the consumption of certain species should be restricted. This study describes key results from an initial study aimed at identifying and quantifying the sources that control c...

We have shown recently that levels of persistent, bioaccumulative contaminants (polychlorinated biphenyls, dioxins, and several chlorinated pesticides) are significantly higher in farmed than in wild salmon and that European farm-raised salmon have significantly greater toxic contaminant loads than those raised in North and South America. In this paper, we extend these results to polybrominated...

Fertilized chicken eggs were injected with environmental doses of 4 chiral polychlorinated biphenyls (PCBs) and 8 polybrominated biphenyl ethers (PBDEs) to investigate their uptake, metabolism in the embryo, and distribution in the neonate chicken. PCB95 uptake was the most efficient (80%) whereas BDE209 was the least (56%). Embryos metabolized approximately 52% of the PCBs absorbed. Though som...

Accidental contamination of the food chain in Michigan in 1973 with polybrominated biphenyls (PBBs) led to the establishment of a registry of exposed individuals in 1976. Serum was collected and analyzed for PBB at the time of enrollment and for targeted studies in the following years. We used the archived PBB data to study the elimination of PBB and to identify factors associated with eliminat...

The distribution of persistent organic pollutants (POPs) within background soil profiles was investigated in boreal (Norway) and montane (Italy) areas. The typical build-up of slowly mineralizing humus layers, containing high amounts of soil organic matter (SOM) makes soils of such ecosystems an important global sink for POPs released to the environment. The study focused on evidence and implic...

To evaluate the biomagnification extent of polybrominated diphenyls ethers (PBDEs) and polychlorinated biphenyls (PCBs) in a highly contaminated freshwater food web from South China, trophic magnification factors (TMFs) for 18 PBDE congeners and 53 PCB congeners were calculated. The TMF values ranged 0.26-4.47 for PBDEs and 0.75-5.10 for PCBs. Forty-five of 53 PCBs and BDEs 47, 100 and 154 had ...

The long-range transport (LRT) of organic chemicals in the environment is reviewed, with particular focus on the role of environmental fate and transport models and the relationship between model results and field data. Results from generic multimedia box models, spatially resolved multimedia box models, and atmospheric transport models are highlighted, including conceptual investigations of co...