Three-dimensional (3D) urchin-like MnO2@poly (sodium 4-styrene sulfonate) (PSS)/poly (diallyl dimethylammonium chloride) (PDDA)/PSS particles were prepared via the layer-by-layer (LBL) assembly of polyelectrolytes for extraction Zn2+ from alkaline media. The adsorption performance on MnO2, MnO2@PSS/PDDA/PSS, and MnO2@(PSS/PDDA)3/PSS was investigated in batch experiments. MnO2@PSS/PDDA/PSS has b...

The asymmetric addition of diazoacetylferrocene to styrene derivatives give optically active cyclopropyl acetylferrocenes (ee up 96%) was carried out using chiral ruthenium porphyrins as homogeneous catalysts. Intermolecular N–H functionalization anilines and amino esters by means carbenoid-induced insertion also observed tetraphenylporphyrin iron chloride catalyst.

Non-invasive collection of target cells is crucial for research in biology and medicine. In this work, we combine a thermo-responsive material, poly(N-isopropylacrylamide), with an electroactive poly(3,4-ethylene-dioxythiopene):poly(styrene sulfonate), to generate smart conductive copolymer the label-free non-invasive detection capture release on gold electrodes by electrochemical impedance spe...

Palladium(II) complexes containing phosphine donor ligands derived from naphthyl(diphenyl)phosphine were synthesized and characterized by NMR and elemental analysis. The complexes were studied as catalyst precursors in the methoxycarbonylation reaction of several aromatic and aliphatic olefins under mild conditions. The catalysts reported high chemoselectivities (over 96%) and regioselectivitie...

A mild catalytic asymmetric direct fluoro-arylation of styrenes has been developed. The palladium-catalyzed three-component coupling of Selectfluor, a styrene and a boronic acid, provides chiral monofluorinated compounds in good yield and in high enantiomeric excess. A mechanism proceeding through a Pd(IV)-fluoride intermediate is proposed for the transformation and synthesis of an sp(3) C-F bond.

Confidence in the extrapolation of animal toxicity data to humans can be enhanced by the application of pharmacokinetic concepts integrated with chronic toxicity data and knowledge of a chemical's mechanism(s) of toxicity. Basic pharmacokinetic concepts (including dose-dependent or Michaelis-Menten kinetics) and their relationship to the risk estimation process are discussed using vinyl chlorid...

Carbon monoxide (CO) and styrene derivatives that can be both generated by a palladium on carbon (Pd/C)-catalyzed carbon-carbon (C-C) bond cleavage reaction of cinnamaldehyde derivatives were effectively utilized in further palladium-catalyzed C-C bond forming reactions in a direct and practical way. CO derived from simple and affordable CO carriers such as cinnamaldehyde or terephthalaldehyde ...

BACKGROUND The ability to present signalling molecules within a low fouling 3D environment that mimics the extracellular matrix is an important goal for a range of biomedical applications, both in vitro and in vivo. Cell responses can be triggered by non-specific protein interactions occurring on the surface of a biomaterial, which is an undesirable process when studying specific receptor-ligan...