Lactic acid is one of the top 30 potential building-block chemicals from biomass, of which the most extensive use is in the polymerization of lactic acid to poly-lactic-acid (PLA). To reduce the cost of PLA, the search for cheap raw materials and low-cost process for lactic acid production is highly desired. In this study, the final titer of produced L-lactic acid reached a concentration of 185...

A general approach for producing biodegradable nanoparticles for sustained nucleic acid release is presented. The nanoparticles are produced by precipitating a water-in-oil microemulsion in supercritical CO(2). The microemulsion consists of a transfer RNA aqueous solution (water phase), dichloromethane containing poly(l-lactic acid)-poly(ethylene glycol) (oil phase), the surfactant n-octyl β-D-...

In this study, we sought to develop strategies for improved endothelialization of a new polymer coating for vascular stents. Surface enhancement of the new poly-1,8-octanediol-co-citric acid (POC) polymer was achieved through conjugation of anti-CD34 antibody and incorporation of vascular endothelial growth factor and basic fibroblast growth factor-containing poly-lactic-co-glycolic acid microp...

In this study, we developed NIR-light responsive poly (lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) by incorporating the ICG dye for local delivery of small-molecular drugs and therapeutics. Since NIR light...

Abstract Wheat bran (WB) was investigated as potential filler for controlling the plasticizer migration in poly(lactic acid) (PLA)/poly(butylene succinate adipate) (PBSA) binary blends (with 60 wt.% of PLA and 40 PBSA). The process three different biobased biodegradable plasticizers [Triacetin (TA), acetyl tri- n -butyl citrate (ATBC) oligomeric lactic acid (OLA)] adding them at a fixed amount ...

Biodegradable four-arm star-shaped poly(lactic acid) (4sPLA) was synthesized from l-Lactic acid (l-LA) and pentaerythritol (PENTA), the polymerization kinetics studied. The effects of reaction time, temperature molar ratio on 4sPLA were discussed. molecular structure characterized by Fourier transform infrared spectroscopy (FTIR) 1H nuclear magnetic resonance spectra (1H-NMR). results showed th...