A fluorimetric immunoassay has been used to assess reactivity of rheumatoid factor (RF) with both histone proteins and other basic polycations (poly-L-lysine, poly-L-ornithine, and protamine) bound to an immobilised tyrosine-glutamic acid polyanionic copolymer. Isolated RF preparations can bind to histone proteins in this assay, notably to H3 and H4 histones, and this activity was always masked...

The aim of this study was to investigate the antibacterial characteristics and antibacterial mechanisms of 3-poly-lysine against Escherichia coli and Staphylococcus aureus. The diameters of inhibition zones of E. coli (10 0.5 mm) and S. aureus (12 0.1 mm) treated by 200 mg/ml 3-poly-lysine were much larger than control (5 0.3 mm) (p < 0.05). Minimum inhibition concentration of 3-poly-lysine aga...

Every year, microbial contamination causes billions of tons food wasted and millions cases illness. ?-Poly- l -lysine has potent, wide-spectrum inhibitory activity is heat stable biodegradable. It been approved for preservation by an increasing number countries. produced from soil bacteria the genus Streptomyces , also producers various antibiotic drugs toxins not considered to be a naturally o...

In contrast to simple salts or negatively charged macromolecules, positively charged proteins and peptides including cytochrome c (yeast) and poly-L-lysine are efficiently encapsulated while inducing the formation of polymersomes from polystyrene(140)-b-poly(acrylic acid)(48) (PS(140)-b-PAA(48)).

Determination of pesticides is important for human health. Sensors are one the best solutions because they do not require a long sample preparation and can be used only in laboratory. Electrochemical sensors easily minimised employed detection liquid samples such as ground or wastewater. Conducting polymers have few roles electrochemical sensors, therefore, good candidates sensor development. E...

Purpose: Psylliumseeds are used in traditional herbal medicine to treat various disorders. Moreover, as a soluble fiber, psyllium has potential to stimulate bacterial growth in digestive system. We aimed to substitute alkali-extractable polysaccharides of psyllium for alginate in beads with second coat of poly-l-lysine to coat Lactobacillus acidophilus. Methods: Beads were prepared using extrus...

Hollow (air-filled) microparticles, i.e., microbubbles, provide a promising novel vehicle for both local delivery of therapeutic agents and simultaneous diagnostic ultrasound echo investigations. In this paper, we describe the synthetic routes for decorating the polymeric shell of a poly(vinyl alcohol)-based microbubble with low and high molecular weight ligands with pharmacological relevance. ...

Bio-functionalized surfaces were prepared to study the adherence and differentiation capacity of neural stem cells derived from human umbilical cord blood (HUCB-NSC). Cell growth platforms containing arranged arrays of adhesive molecules were created by microcontact printing on a biologically inert surface. Biomolecules used to prepare microarray platforms included the extracellular matrix prot...