Chinese hamster ovary (CHO) cells are currently the workhorse of the biopharmaceutical industry. However, yeasts such as Pichia pastoris are about to enter this field. To compare their capability for recombinant protein secretion, P. pastoris strains and CHO cell lines producing human serum albumin (HSA) and the 3D6 single chain Fv-Fc anti-HIV-1 antibody (3D6scFv-Fc) were cultivated in comparab...

Let d ≥ 3 be an integer and p a prime coprime to d. Let Q and Qp be the algebraic closure of Q and Qp respectively. Let Zp be the ring of integers of Qp. Suppose f(x) is a degree-d polynomial in (Q ∩ Zp)[x]. Let Q(f) be the number field generated by coefficients of f in Q. Let P be a prime ideal in the ring of integers OQ(f) of Q(f) lying over p, with residue field Fq for some p-power q. Let A ...

In this paper, by the studying of the Gauss map, Laplacian operator, curvatures of surfaces in R 1 and Bour’s theorem, we are going to identify surfaces of revolution with pointwise 1-type Gauss map property in 3−dimensional Minkowski space. Introduction The classification of submanifolds in Euclidean and Non-Euclidean spaces is one of the interesting topics in differential geometry and in this...

In this paper, we show that a pointwise symmetric pre-isotonic preclosure function is uniquely determined the pairs of sets it separates. We then show that when the preclosure function of the domain is pre-isotonic and the pre-closure function of the codomain is pre-isotonic and pointwise-pre-symmetric, functions which separate only those pairs of sets which are already separated are precontinu...

This report proposes a novel optimization algorithm for learning support vector machines (SVM) classifiers with structured output spaces introduced recently by Tsochantaridis et. al. Learning structural SVM classifier leads to a special instance of quadratic programming (QP) optimization with a huge number of constraints. The number of constraints is proportional to the cardinality of the outpu...

In this paper, we prove the existence of a random fixed point of by using pointwise asymptotically nonexpansive random operator and the stability resultsof two iterative schemes for random operator.