the antimicrobial activity of some novel ascorbic acid-metal complexes [bisascorbate complexes of copper (ii), zinc(ii), manganese (11), iron (111), cobalt(ii), lead(ii) and cadmium(ii)] was investigated. four standard strains of bacterial species - staphylococcus aureus, escherichia coli, bacillus subtilis and klebsiella pneumonia and four fungal species - trichophyton sp. penicillium sp., asp...

the objectives of this experiment were to investigate the application of new ligands including different atoms & evaluation their nucleophile effects against various metals. chemistry researchers are really interested in this field. from among various ligands, there are some ligands with different coordinating ligands as well. there are great number of intermediate complexes and major eleme...

We have prepared and characterized a few Mn (III) complexes by using a few bidentate and tridentate ligands. Spectra of the manganese (Abstract We have prepared and characterized a few Mn (III) complexes by using a few bidentate and tridentate ligands. Spectra of the manganese (III) ion in a variety of molecular environments are reported . On the basis of solution spectra, some of these co...

Domperidone is a widely used antiemetic, poorly water soluble drug, erratically absorbed in stomach and possess several dissolution-related problems thus it has poor bioavailability. Solubility of a drug plays a very important role in dissolution and hence absorption of drug which ultimately affects its bioavailability. Hence, by considering the facts related to drug, attempts have been made to...

Domperidone is a widely used antiemetic, poorly water soluble drug, erratically absorbed in stomach and possess several dissolution-related problems thus it has poor bioavailability. Solubility of a drug plays a very important role in dissolution and hence absorption of drug which ultimately affects its bioavailability. Hence, by considering the facts related to drug, attempts have been made to...

Introduction: The chemistry of metal complexes derived from heterocyclic compounds has attracted considerable interest due to the broad range of pharmacological activities of such compounds. The important pathogens such as Escherichia coli, and Staphylococcus aureus are wildly caused many diseases. So antibacterial activity of Zn (Ⅱ), Ni (Ⅱ), Co (Ⅱ) and Cu (Ⅱ) chromone complexes against two kin...

The complexation reactions between N,N'-3,6-dioxa-1,8-octanebis (salicylaldimine) [saldioxen(I)] and Mn(II), Co(II), Ni(II), Cu(II), Zn(II), Cd(II) and Hg(II) were studied spectrophotometrically in methanol solution at 25 °C. The stoichiometry of the complexes were obtained as 2:1 and 1:1 sadioxen-metal ion using mole ratio method. The formation constants of the complexes were determined, a...

keeping in view the promising potential of carbonic anhydrase inhibitor based antimicrobials and enhancement of carbonic anhydrase inhibitory activity by metal complexes of sulfonamides, with an aim to develop better antimicrobial agents we have attempted investigation of antimicrobial activity of metal complexes of 4-(2'-hydroxy phenyl imino) phenyl sulphonamide. sulfanilamide was taken a...

the in-situ method of synthesis has been used to isolate oxovanadium(iv) complexes with ligands derived by reaction of benzil with amino acids such as glycine, alanine, serine, cysteine and valine, where template effect of vo +2 cation appears to play an important role. the complexes are characterised by elemental analysis, magnetic moment measurements and spectral (infrared, electronic and ele...