The platinum-based anticancer drugs cisplatin, carboplatin, and oxaliplatin are an important component of chemotherapy but are limited by severe dose-limiting side effects and the ability of tumors to develop resistance rapidly. These drugs can be improved through the use of drug-delivery vehicles that are able to target cancers passively or actively. In this study, we have tethered the active ...

The vibrational spectra of platinum nanoparticles (12 nm) capped with tetradecyltrimethylammonium bromide, C(14)TAB, were investigated by Fourier transform infrared (FTIR) spectroscopy. We have shown that the thermal decay of Pt-C(14)TAB nanoparticles in N(2), H(2), and O(2) atmospheres leads to the release of the hydrocarbon chain of the surfactant and the formation of a strongly bonded layer ...

The use of an engineered variant of a plant virus, Cowpea mosaic virus (CPMV), as a template for directed mineralization provides an environmentally benign route to monodisperse iron-platinum nanoparticles of approximately 30 nm diameter.

Supramolecular self-assembled nanoparticles that can overcome cisplatin resistance were constructed by utilizing a platinum(IV) prodrug bridged β-cyclodextrin dimer and adamantyl group modified porphyrin as the host and guest molecules, respectively.

A novel route has been developed to fabricate ordered carbon mesoporous materials with well-dispersed, highly stable Pt nanoparticles of ca. 2-3 nm on the pore walls using platinum acetylacetonate as the co-feeding carbon and Pt precursor.

A highly sensitive and stable [Ru(bpy)3]2+ ECL sensor has been fabricated based on the multilayer films of Nafion-stabilized magnetic nanoparticles (Nafion/Fe3O4) formed on a platinum electrode surface by means of an external magnet.

The cathodic dissolution of platinum, resulting from the oxygen reduction reaction (ORR) or hydrogen peroxide reduction on platinum, has been investigated. Highly oxidizing hydroxyl radicals (OH•) are believed to be the species responsible for the platinum dissolution phenomenon. These radicals are produced from the ORR byproduct, hydrogen peroxide, through a 1 electron reduction pathway (H2O2 ...

Platinum nanoparticles are being utilized in various industrial applications, including in catalysis, cosmetics, and dietary supplements. Although reducing the size of the nanoparticles improves the physicochemical properties and provides useful performance characteristics, the safety of the material remains a major concern. The aim of the present study was to evaluate the biological effects of...

The electrocatalytic properties of nanoparticles depend on their size, shape and composition. These properties are typically probed by measuring the total electrocatalytic reaction current of a large number of nanoparticles, but this approach is time-consuming and can only measure the average catalytic activity of the nanoparticles under study. However, the identification of new catalysts requi...