BACKGROUND Wound healing involves complex mechanisms, which, if properly chaperoned, can enhance patient recovery. The abilities of platelets and keratinocytes may be harnessed in order to stimulate wound healing through the formation of platelet clots, the release of several growth factors and cytokines, and cell proliferation. The aim of the study was to test whether autologous keratinocyte s...

Platelet-rich fibrin (PRF) belongs to a new generation of platelet concentrates, with simplified processing and without biochemical blood handling. In this fourth article, investigation is made into the previously evaluated biology of PRF with the first established clinical results, to determine the potential fields of application for this biomaterial. The reasoning is structured around 4 funda...

Platelet-rich fibrin (PRF) belongs to a new generation of platelet concentrates geared to simplified preparation without biochemical blood handling. In this initial article, we describe the conceptual and technical evolution from fibrin glues to platelet concentrates. This retrospective analysis is necessary for the understanding of fibrin technologies and the evaluation of the biochemical prop...

l P ( p u d F m S P r B t e l ( b P W i p p a latelet-rich plasma (PRP) is an autologous concentraion of human platelets in a small volume of plasma. herefore, the term PRP is preferred to autologous latelet gel, plasma-rich growth factors (PRGFs), or a ere autologous platelet concentrate. Because it is a oncentration of platelets, it is also a concentration of he 7 fundamental protein growth f...

background autologous platelet concentrate has been used to improve the function and regeneration of injured tissues. tendinopathies are common in clinical practice, although long-term treatment is required. on the basis of lead time, we compared the effect of using platelet-rich plasma (prp) and platelet-rich fibrin (prf) in repairing rat achilles tendon. methods the effectiveness of using prp...

This study analyzed the effect of the platelet count in platelet-rich plasma (PRP) on bone regeneration in vivo. Twenty male New Zealand white rabbits were used. PRP was produced using the Platelet Concentrate Collection System (PCCS) (3i, Miami, FL, USA). After inducing ketamine-xylazine anaesthesia, a self-tapping titanium screw (Branemark MK III TiUnite, 3.75 x 7 mm) was inserted in each dis...

Platelet-rich fibrin, developed in France by Choukroun et al., is a second generation platelet concentrate widely used to accelerate soft and hard tissue healing. It is a strictly autologous fibrin matrix containing a large quantity of platelet and leukocyte cytokines. It has also been shown to stimulate the growth of osteoblasts and periodontal ligament cells, both of which are significant for...