BACKGROUND Although medical textbooks usually classify fasting plasma glucose <70 or 80 mg/dL (<3.89 or 4.44 mmol/L) as abnormal, the prognosis for patients with low fasting plasma glucose is unclear. METHODS AND RESULTS We conducted prospective cohort studies among 40 069 men and women to investigate the association between fasting plasma glucose levels and cardiovascular disease and all-cau...

The effects of incorporating Fybogel (3.5 and 7 g doses), Metamucil (7 g) or guar gum (2.5 and 14.5 g doses) in a drink containing 50 g glucose on plasma glucose, plasma insulin and gastric emptying were studied in thirty-eight normal volunteers. In addition, the effects of Fybogel (7 g) on glucose tolerance, plasma insulin and gastric emptying were measured in fourteen non-insulin-dependent di...

background and aim: in skeletal muscle, carnitine plays an essential role in the translocation of long-chain fatty-acids into the mitochondrial matrix for subsequent beta-oxidation. despite an abundance of literature describing the basic mechanisms of action of l-carnitine metabolism, there remains some uncertainty regarding the effects of oral l-carnitine supplementation on metabolism and exer...

The effects of preexercise hyperinsulinemia on exercising plasma glucose, plasma insulin, and metabolic responses were assessed during 50 min cycling at 62% VO2max. Subjects were fed a 6% sucrose/glucose solution (LCHO) or a 20% maltodextrin/glucose solution (HCHO) to induce changes in plasma insulin. During exercise, subjects assessed perceived nauseousness and light-headedness. By the start o...

vaspin as a novel adipokine has insulin-sensitizing effects, which may be associated with decreased blood glucose concentration. in this study, we aimed to investigate the effects of resistance exercise training on plasma vaspin concentrations and its relation to plasma levels of insulin and glucose in patients with type 2 diabetes (t2d). in a quasi-experimental study, 18 male patients with t2d...

background hypovitaminosis d has been associated with the development of gestational diabetes mellitus (gdm) in many observational studies. objectives we report the first study of the impact of prenatal vitamin d supplementation on postpartum dysglycemia in gdm patients in a randomized clinical trial. patients and methods women with gdm at 12 - 32 weeks of gestation were assigned randomly to ei...

Introduction: Current study examined the possible role of the central nucleus of amygdala (CeA) transient inactivation on the metabolic and hormonal disturbances induced by acute electro foot shock stress in female rats. Considering the differences between female and male in responses to stress, this study attempts to reveal possible mechanisms underlying these differences. Methods: Uni- or bil...