BACKGROUND A pit latrine is the most basic form of improved sanitation which is currently used by a number of people around the globe. In spite of the wide spread use, known successes and advantages associated with pit latrines, they have received little attention in form of research and development. This review focuses on the usage and performance (filling, smell and insect nuisance) of pit la...

The POU transcription factor Pit-1 activates members of the prolactin/growth hormone gene family in specific endocrine cell types of the pituitary gland. Although Pit-1 is structurally conserved among vertebrate species, evolutionary changes in the pattern of Pit-1 RNA splicing have led to a notable "contraction" of the transactivation domain in the mammalian lineage, relative to Pit-1 in salmo...

Macular detachment causes visual deterioration in 25-75% of patients with congenital optic disc pit. A number of treatment options have been reported to manage the macular detachment in optic pit. An optic disc pit represents a defect in the lamina cribrosa; theoretically, an ideal procedure to treat optic pit associated macular detachment would be one that prevents the flow of fluid across the...

A critical component in determining post-mining pit water quality is knowledge of groundwater fluxes, both as the pit fills and after steady state conditions have been reached. Simulations of the filling of an open pit in Crescent Valley, Nevada, were made to generate inputs for pit lake chemistry predictions. The simulations show that the water table recovery is most rapid immediately after pu...

BACKGROUND/AIM The aim of this study was to examine the relationship between narrow-band imaging (NBI) magnifying observation using the surface pattern as the main evaluation criterion and pit pattern diagnosis on the basis of magnifying observation using a dye in relation to the characteristics of colorectal tumors according to their morphologies. METHODS In this study, NBI observation and p...

The homeodomain protein Pit-1 cooperates with the basic-leucine zipper protein CCAAT/enhancer binding protein alpha (C/EBPalpha) to control pituitary-specific prolactin gene transcription. We previously observed that C/EBPalpha was concentrated in regions of centromeric heterochromatin in pituitary GHFT1-5 cells and that coexpressed Pit-1 redistributed C/EBPalpha to the subnuclear sites occupie...

In this study, a hybrid intelligent model has been designed to predict groundwater inflow to a mine pit during its advance. Novel hybrid method coupling artificial neural network (ANN) with genetic algorithm (GA) called ANN-GA, was utilised. Ratios of pit depth to aquifer thickness, pit bottom radius to its top radius, inverse of pit advance time and the hydraulic head (HH) in the observation w...

Methane ebullition from lakes is an important contributor to atmospheric greenhouse gases. However, typically sampled at intervals greater than the duration of events, limiting our understanding factors controlling this flux. Here, we present high-frequency data a single site in boreal pit lake during open-water season between June 24 and 21 October 2018. We record every 30 min for first 2 mont...

The homeodomain (HD) protein Pit-1 cooperates with the basic-leucine zipper (b-ZIP) protein CCAAT/enhancer binding protein alpha (C/EBPα) to control pituitary-specific prolactin (PRL) gene transcription. We previously observed that C/EBPα was concentrated in regions of centromeric heterochromatin in pituitary GHFT1-5 cells and that co-expressed Pit-1 redistributed C/EBPα to the subnuclear sites...