نتایج جستجو برای: piperacillin

تعداد نتایج: 2563  

Journal: :The Journal of antimicrobial chemotherapy 1993
Y Mouton O Leroy C Beuscart C Chidiac E Senneville F Ajana P Lecocq

An open, non-comparative multicentre study was conducted at 36 sites in six countries to test the efficacy and safety of piperacillin/tazobactam in the therapy of lower respiratory tract infections. Piperacillin 4 g and tazobactam 500 mg were administered intravenously every 8 h for a minimum of five days. Two hundred and thirty patients were enrolled: 133 were evaluable for clinical efficacy a...

Journal: :The Journal of infectious diseases 2004
Louis B Rice Viera Lakticová Marion S Helfand Rebecca Hutton-Thomas

We compared ceftriaxone and piperacillin-tazobactam at doses ranging from 0.1 to 2 times the human equivalent daily dose (HEDD), to determine their impact on gastrointestinal colonization by ampicillin- and vancomycin-resistant Enterococcus faecium C68 in a mouse model. Ceftriaxone failed to promote colonization at doses up to 0.25 times the HEDD, whereas piperacillin-tazobactam promoted coloni...

2003
RICHARD H. GLEW

The stability of the aminoglycosides gentamicin, tobramycin, and amikacin stored in combination with carbenicillin, piperacillin, cefotaxime, and moxalactam was evaluated at four temperatures (25, 4, -8, and -70°C) over a 3-week period. Amikacin was the most stable of the aminoglycosides and demonstrated no loss of activity when stored with either carbenicillin or piperacillin. Gentamicin and t...

Journal: :Antimicrobial agents and chemotherapy 1994
S J Incavo P J Ronchetti J H Choi H Wu M Kinzig F Sörgel

The penetration characteristics of piperacillin-tazobactam into cortical and cancellous bone tissues were investigated in 10 patients undergoing total hip replacement. The concentration ratios of piperacillin/tazobactam were 9.4 +/- 1.8 in cancellous bone tissue and 8.0 +/- 2.2 in cortical bone tissue, which were close to the 8:1 ratio of drugs administered. The mean ratios of drug concentratio...

2003
ROSEMARY A. PAVUK

The stability of the aminoglycosides gentamicin, tobramycin, and amikacin stored in combination with carbenicillin, piperacillin, cefotaxime, and moxalactam was evaluated at four temperatures (25, 4, -8, and -70°C) over a 3-week period. Amikacin was the most stable of the aminoglycosides and demonstrated no loss of activity when stored with either carbenicillin or piperacillin. Gentamicin and t...

Journal: :Asian Pacific journal of tropical biomedicine 2014
Hakan Söyüt Elif Duygu Kaya Sükrü Beydemir

OBJECTIVE To investigate the in vitro effects of the antibacterial drugs, meropenem trihydrate, piperacillin sodium, and cefoperazone sodium, on the activity of human serum paraoxonase (hPON1). METHODS hPON1 was purified from human serum using simple chromatographic methods, including DEAE-Sephadex anion exchange and Sephadex G-200 gel filtration chromatography. RESULTS The three antibacter...

Journal: :Antimicrobial agents and chemotherapy 1983
R H Glew R A Pavuk

The stability of the aminoglycosides gentamicin, tobramycin, and amikacin stored in combination with carbenicillin, piperacillin, cefotaxime, and moxalactam was evaluated at four temperatures (25, 4, -8, and -70 degrees C) over a 3-week period. Amikacin was the most stable of the aminoglycosides and demonstrated no loss of activity when stored with either carbenicillin or piperacillin. Gentamic...

Journal: :The Journal of antibiotics 1991
Y Minami M Komuro K Sakawa N Ishida K Matsumoto K Oishi

metabolites in human. In the course of clinical study for the coadministration ofPIPC with a /Mactamase inhibitor, tazobactam3), an active metabolite ofPIPC (1) which is distinct from T-1220A was found in human plasma and urine. The metabolite 1 was also found in the same manneron the administration of PIPCalone, suggesting that the metabolism of PIPC was not affected by the co-administration o...

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