The mouse mammary tumor virus (MMTV) encodes within the U3 region of the long terminal repeat (LTR) a protein known as the superantigen (Sag). Sag is needed for the efficient transmission of milk-borne virus from the gut to target tissue in the mammary gland. MMTV-infected B cells in the gut express Sag as a type II transmembrane protein that is recognized by the variable region of particular b...

We develop a simple routine unifying the analysis of several important recently-developed stochastic optimization methods including SAGA, Finito, and stochastic dual coordinate ascent (SDCA). First, we show an intrinsic connection between stochastic optimization methods and dynamic jump systems, and propose a general jump system model for stochastic optimization methods. Our proposed model reco...

Our recent study showed that SAG/RBX2 E3 ubiquitin ligase regulates apoptosis and vasculogenesis by promoting degradation of NOXA and NF1, and co-operates with Kras to promote lung tumorigenesis by activating NFκB and mTOR pathways via targeted degradation of tumor suppressive substrates including IκB, DEPTOR, p21 and p27. Here we investigated the role of Sag/Rbx2 E3 ligase in cellular senescen...

the rice industry to 1) estimate the milling yield that may be expected of rice lots when milled in large-scale milling systems and 2) produce milled rice samples from which visual, functional, sensory and nutritional assessments of the rice lot can be made. This chapter presents factors that can affect the laboratory measurement of rice milling yield, focusing on the use of the McGill #2 rice ...

L aboratory milling systems are used throughout the rice industry to 1) estimate the milling yield that may be expected of rice lots when milled in large-scale milling systems and 2) produce milled rice samples from which visual, functional, sensory and nutritional assessments of the rice lot can be made. This chapter presents factors that can affect the laboratory measurement of rice milling ...

the effect of hydraulic retention time in a range from 1.0-5.5 days was evaluated in a laboratoryscaleanaerobic fixed bed reactor packed with a hybrid material composed of tire rubber and zeolite. underthese conditions, cod removal efficiencies varied from 28.3% to 82.1%, respectively. over the more than 6months of operation, no clogging was observed. the results obtained demonstrated that this...

PURPOSE Sensitive to apoptosis gene (SAG; also known as RBX2 or ROC2) was originally cloned as a redox-inducible antioxidant protein and was later characterized as a RING component of SCF E3 ubiquitin ligases. SAG overexpression inhibits apoptosis induced by many stimuli both in vitro and in vivo. SAG mRNA was overexpressed in human lung tumor tissues with a correlation to poor patient survival...

Voltage sag compensator is very important in power quality. Its performance also depends on the types of sag detection techniques used. Sag detection technique determines the dynamic performance of a voltage-sag compensator. Many techniques have been introduced to measure and to detect voltage sag, such as RMS-Value Evaluation and Peak-Value Evaluation. Unfortunately, most of the techniques req...

Fine and ultrafine grinding of limestone are frequently used in the pharmaceutical, chemical, construction, food, cosmetic industries, however, research investigations have not yet been published on combination energy life cycle modeling. Therefore, first aim this work was examination main parameters particles to determine an empiric energy-model. Dry wet experiments carried out with a Bond mil...

Suitable voltage sag objectives are not yet found in any standard document. One of the reasons for the lack of objectives is the difficulty of defining suitable site sag indices. In this paper present sag characterisation methods are reviewed and discussed. The University of Wollongong sag index is summarized which shows a better way of characterizing voltage sags. A new method is then given fo...