Calcifying cystic odontogenic tumors (CCOTs) are benign cystic tumors that form abnormally keratinized ghost cells. Mutations in CTNNB1, which encodes beta-catenin, have been implicated in the development of these tumors, but a causal relationship has not been definitively established. Thus, mutational hot spots in 50 cancer genes were examined by targeted next-generation sequencing in 11 sampl...

OBJECTIVE Although the relationship between the therapeutic alliance and outcome has been supported consistently across several studies and meta-analyses, there is less known about how the patient and therapist contribute to this relationship. The purpose of this present meta-analysis was to (1) test for therapist effects in the alliance-outcome correlation and (2) extend the findings of previo...

arising from the hair matrix (1-3). The preoperative diagnosis of this entity may be difficult because of its multiple manifestations (1), especially if the examining physician is unfamiliar with them. There have been some reports in the radiological literature which included the CT (2, 4, 5) and MR (2, 6-8) imaging findings of pilomatricoma however, to the best of our knowledge, there have bee...