A new series of fluorinated quinoline -1,4-dithiones 3(a-f) were obtained by the treatment 3-aryl-2-hydrazino-quinolines 1(a-f) with isobenzo furan-1,3-dithione 2 in presence p- toluene sulphonic acid (PTSA) solid state at room temperature as one pot. All products are monitored TLC and isolated GC furthermore confirmed spectral analysis.

This article describe the applicability of 1,4-disulfopiperazine-1,4-diium chloride ([Piper-(SO3H)2].2Cl) as a green, versatile and Brönsted acidic ionic catalyst in the promotion of the synthesis of phthalazine derivatives via one-pot three component reaction between aromatic aldehydes, 1,3-diketone derivatives and phthalhydrazide under solvent-free reaction cond...

The Brønsted acidic ionic liquid ([BMIm]HSO4) catalyzed three-component synthesis of 2H-indazolo[2,1-b]phthalazine-trione derivatives at room temperature. The integrity of the ionic liquid remains reasonably unchanged when it is separated from the reaction mixture by water extraction, as it can be recycled several times without any loss of activity in each of the title syntheses. The products a...

An eco-safe and facile multi-component domino reaction has been described for the synthesis of 1H-pyrazolo [1, 2-b] phthalazine-5, 10-dione derivatives. The products were obtained by a four-component condensation reaction between phthalimide, hydrazine monohydrate, aromatic aldehyde derivatives and malononitrile in the presence of a catalytic amount of copper (II) oxide (CuO) ...

Air-sensitive complexes [Cu2(μ-phtz)3(PR3)2][CF3SO3]2 (phtz = C8H6N2), 3 (R = phenyl) and 4 (R = benzyl) have been synthesized from {[Cu(CF3SO3)]2·C6H5Me} (1) at room temperature, in acetonitrile solution, after successive additions of stoichiometric amounts of phthalazine (phtz) and triphenylphosphine and tribenzylphosphine, respectively. The dissolution of 4 in an excess of benzyl chloride ga...

Chemiluminescence (CL) of a cyclometallated iridium (III) complex {tris[1-(2,6-dimethylphenoxy)-4-(4-chlorophenyl)phthalazine]iridium(III)} in the presence of potassium permanganate and oxalic acid is reported for the first time. Cysteine exhibits sufficient enhancing effect on the CL generated from the cyclometallated iridium(III) complex, which make it possible for the sensitive detection of ...

A series of cycloalkene-annelated phthalazin-1(2H)-ones (2-5) was prepared in high yields by a one-pot procedure, employing pyridazino[4,5-d]pyridazin-1(2H)-ones (1) as azadienes and cyclic enamines as dienophiles in an inverse-electron-demand Diels-Alder reaction, followed by acid-catalyzed aromatization. Phthalazin-1(2H)-ones bearing a substituent at C-4 represent key intermediates in the syn...