Conway, T. W. (The University of Texas, Austin), E. M. Lansford, Jr., and W. Shive. Influence of phenylalanine analogues upon bacterial accumulation and incorporation of phenylalanine. J. Bacteriol. 85:141-149. 1963.-Phenylalanine accumulation and its relation to phenylalanine incorporation into trichloroacetic acid-insoluble material in Escherichia coli 9723 were studied with a variety of stru...

The aim of this research was the comparative study content amino acids in herb and tubers Stachys sieboldii. acid composition raw materials carried out using high-performance liquid chromatography (HPLC). results obtained have shown that aerial parts plants investigated higher than underground organs. Free bound L-aspartic acid, L-proline, L-phenylalanine were present analyzed samples greatest ...

To investigate whether splanchnic uptake of the indicator amino acid ([1-(13)C] phenylalanine) during the fed state alters the estimate of lysine requirement, five healthy men were studied at graded levels of lysine intake, with either an oral or intravenous (IV) tracer protocol, in a randomized, crossover design. Splanchnic extraction of the oral tracer was expressed as the difference between ...

Muscle protein synthesis requires energy and amino acids to proceed and can be stimulated by insulin under certain circumstances. We hypothesized that short-term provision of insulin and nutritional energy would stimulate muscle protein synthesis in healthy subjects only if amino acid availability did not decrease. Using stable isotope techniques, we compared the effects on muscle phenylalanine...

We have recently seen a baby girl with gross mental deficiency who had repeated attacks of generalized oedema. She also had an extremely unpleasant, pungent smell due to the presence in her urine of a substance derived from ox-hydroxy-butyric acid. So far as we know, this acid has not previously been detected in human urine. The urine also contained phenylpyruvic acid and phenylacetic acid as w...

The phenylalanine inhibition of skeletal muscle pyruvate kinase has been further studied. Even at high levels of the inhibitor the plots of reaction rates as a function of phosphoenolpyruvate concentration give hyperbolic curves; the inhibition by phenylalanine is of the mixed type. The enzyme exhibits a homotropic cooperative effect with respect to this inhibitor. This property is strongly dep...

The project is comparing two types of calculation derived graphene. Which one of these carbon graphene linked to the phenylalanine amino acid from the acidic site (-COOH) and another from the base site (-NH2). For this purpose, at first the material contained in the both sides of reaction were geometrically optimized, then the calculation of the thermodynamic parameters performed on ...

Muscle protein synthesis was measured by infusion of L-[2H(5)]phenylalanine in two groups of anesthetized dogs, before and during infusion of insulin with euaminoacidemia, and with differing concentrations of unlabeled phenylalanine (tracee). With the infusion of insulin, muscle protein synthesis increased 39 +/- 12% based on phenylalanyl-tRNA. Calculation with plasma phenylalanine enrichment o...

We have recently seen a baby girl with gross mental deficiency who had repeated attacks of generalized oedema. She also had an extremely unpleasant, pungent smell due to the presence in her urine of a substance derived from ox-hydroxy-butyric acid. So far as we know, this acid has not previously been detected in human urine. The urine also contained phenylpyruvic acid and phenylacetic acid as w...

Tumor necrosis factor-alpha (TNFα) is a multifunctional cytokine associated with inflammation, immune responses, and autoimmune diseases including rheumatoid arthritis, inflammatory bowel disease, psoriasis. In the present study, we performed in vitro selection, systematic evolution of ligands by exponential enrichment (SELEX) against human TNFα from mRNA-displayed peptide library prepared Esch...