INTRODUCTION A physical 3-dimensional phantom that simulates PET/SPECT images of static regional cerebral blood flow in grey matter with a realistic head contour has been developed. This study examined the feasibility of using this phantom for evaluating PET/SPECT images. METHODS The phantom was constructed using a transparent, hydrophobic photo-curable polymer with a laser-modelling techniqu...

Hybrid imaging is becoming a popular technology in nuclear medicine. We have evaluated the added value of an integrated SPECT/low-dose multislice CT over conventional planar/SPECT nuclear imaging. Phantom and clinical studies were performed on the InfiniaTM HawkeyeTM 4 slice (HWK-4) with an upgraded software package (Xeleris 2.05v) from GE Heatlthcare to assess 1) the benefit of CT for contrast...

abtract background: in nuclear medicine, phantoms are mainly used to evaluate the overall performance of the imaging systems and practically there is no phantom exclusively designed for the evaluation of the software performance.  in this study the hoffman brain phantom was used for quantitative evaluation of reconstruction techniques. the phantom is modified to acquire tomographic and planar i...

Patient motion is inevitable in SPECT and PET due to the lengthy period of time patients are imaged. The authors hypothesized that the use of external-tracking devices which provide additional information on patient motion independent of SPECT data could be employed to provide a more robust correction than obtainable from data-driven methods. Therefore, the authors investigated the Vicon MX vis...

UNLABELLED SPECT with (18)F-FDG has emerged as an alternative to dedicated PET for the assessment of myocardial viability. However, whether FDG SPECT can reliably quantify the extent of viable and scarred myocardium is uncertain. The aim of this study was to investigate whether SPECT with an (18)F-labeled agent would provide information on defect size similar to that provided by dedicated PET. ...

BACKGROUND After yttrium-90 ((90)Y) microsphere radioembolization (RE), evaluation of extrahepatic activity and liver dosimetry is typically performed on (90)Y Bremsstrahlung SPECT images. Since these images demonstrate a low quantitative accuracy, (90)Y PET has been suggested as an alternative. The aim of this study is to quantitatively compare SPECT and state-of-the-art PET on the ability to ...

  Introduction: Although PET scanning using F-18[FDG] is considered the superior radiotracer for tumnor imaging, Gallium-67 is still in use for some malignancies such as lymphoma and hepatoma. One of the strategies to improve the diagnostic accuracy of Gallium is to perform SPECT which is reported to be more sensitive compared to planar imaging. In this study we compa...

PURPOSE This work is a preliminary study of a stationary cardiac SPECT system. The goal of this research is to propose a stationary cardiac SPECT system using segmented slant-hole collimators and to perform computer simulations to test the feasibility. Compared to the rotational SPECT, a stationary system has a benefit of acquiring temporally consistent projections. The most challenging issue i...

Conventional single photon emission computed tomography (SPECT) relies on mechanical collimation whose resolution and sensitivity are interdependent, the best performance a SPECT system can attain is only compromise of these two equally desired properties. To simultaneously achieve high sensitivity, we propose to use sensitive detectors constructed in multi-layer inter spaced mosaicdetectors (M...

discussion the reason is that we assess the relative and not absolute differences of the tracer uptake in this imaging modality. there may be other findings on mpi images which could help us overcome this pitfall, including detecting wall motion abnormalities, lung uptake of the tracer, or transient ischemic dilation. another important issue is the ecg changes during exercise stress testing, wh...