Journal:
:iranian journal of pharmaceutical research
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abbas rezaeian mehrabadi department of pharmacology and toxicology, faculty of pharmacy, shiraz university of medical sciences, shiraz, iran
akram jamshidzadeh pharmaceutical sciences research center, and department of pharmacology and toxicology, faculty of pharmacy, shiraz university of medical sciences, shiraz, iran
marzieh rashedinia department of pharmacology and toxicology, faculty of pharmacy, shiraz university of medical sciences, shiraz, iran
hossein niknahad pharmaceutical sciences research center, and department of pharmacology and toxicology, faculty of pharmacy, shiraz university of medical sciences, shiraz, iran
pioglitazone (pg) is one of thiazolidinediones used for the treatment of type ii diabetes mellitus. some reports of its hepatotoxicity exist, but the mechanism of its hepatotoxicity is not well known. in the present study, the protective effect of some atp suppliers are investigated against mitochondrial toxicity of pg in isolated rat mitochondria. mitochondrial viability was investigated by mt...
