We present a perfusion culture system with miniature bioreactors and peristaltic pumps. The bioreactors are designed for perfusion, live-cell imaging studies, easy incorporation of microfabricated scaffolds, and convenience of operation in standard cell culture techniques. By combining with miniature peristaltic pumps-one for each bioreactor to avoid cross-contamination and to maintain desired ...

This study presents a double-side diaphragm peristaltic pump for efficient medium transport without the unwanted backflow and the lagging effect of a diaphragm. A theoretical model was derived to predict the important parameter of the micropump, i.e., the motion of the valves at large deformations, for a variety of air pressures. Accordingly, we proposed an easy and robust design to fabricate a...

Peristaltic pumping is a mechanism for transporting fluid or immersed particles in a channel by waves of contraction. It occurs in many biological organisms as well as in several human designed systems. In this study, we investigate numerically the peristaltic pumping of an incompressible viscoelastic fluid using the simple Oldroyd-B model coupled to the Navier-Stokes equations. The pump’s wall...

This paper proposes a novel flow-batch analyzer (FBA), which employs a compact, low-cost aquarium air pump as an alternative to a peristaltic pump. The feasibility of using this simple propulsion device is demonstrated in a case study involving the classification of citrus juice samples with respect to brand. For this purpose, UV-vis spectra and SIMCA (soft independent modelling of class analog...

To study the relationships between gastric antral and proximal duodenal motor activity, and the movement of liquid across the pylorus, 10 healthy volunteers were given a test meal of dilute orange juice and bran, and events at the gastric outlet monitored by real-time ultrasound. A total of 116 complete gastric peristaltic cycles were observed and in 86% of these, associated proximal duodenal c...

This paper presents lumped-parameter simulation of dynamic characteristics of peristaltic micropumps. The pump consists of three pumping cells connected in series, each of which is equipped with a compliant diaphragm that is electrostatically actuated in a peristaltic sequence to mobilize the fluid. Diaphragm motion in each pumping cell is first represented by an effective spring subjected to h...

Background: It is not clear whether the use of volumetric peristaltic infusion pumps, affect the quality of the erythrocytes during packed cell transfusion or not. In the present study in vitro quality of red blood cells was assessed after using this type of infusion pumps in a prospective study. Materials and Methods: In this study 60 units of packed red cells were examined before and after p...