In this paper, I begin by suggesting digital photographic images should be considered as being neither a purely visual experience nor a purely perceptual one. Instead, I argue these may be somewhat limiting terms which confine our engagement with images to traditional linguistic interpretations. At a time when digital images are more amenable and liable to forms of recombination, fragmentation ...

Recently, the Hungarian Geographical Bulletin – that had been a forum for introducing empirically focused papers covering various social and physical geographical issues for decades – became engaged increasingly in academic discourses on socio-spatial inequalities, embracing various approaches and problems with diff erent scalar foci. The theoretical and methodological diversity that ranged fro...

This study aims to measure age-friendliness based on the walkability indices of older people urban facilities in sample area Istanbul, Turkey and various districts within. It focuses three key age-friendly cities: open public spaces, health services basic needs; Quantitative datasets are also utilised order environment. There two main quantitative dimensions study: generate accessible areas ide...

TCRs alive on the periphery eeping T cell receptors (TCRs) away from the center of the immunological synapse boosts stimulatory stignals, based on work from The immunological synapse—the cell–cell junction between a T cell and antigen-presenting cell (APC)—looks like a bull's eye, with a central cluster of TCRs and their bound antigen–MHC ligands surrounded by a ring of adhesion molecules and t...

GAL genes and other activated yeast genes remain tethered to the nuclear periphery even after transcriptional shutoff. To identify factors that affect this tethering, we designed a plasmid-based visual screen. Although many factors affected GAL tethering during transcription, fewer specifically affected posttranscriptional tethering. Tw o of these, Rrp6p and Lrp1p, are nuclear exosome component...

In Saccharomyces cerevisiae, genes near telomeres are transcriptionally repressed, a phenomenon termed telomere position effect (TPE). Yeast telomeres cluster near the nuclear periphery, as do foci of proteins essential for TPE: Rap1p, Sir2-4p, and yKu70p/yKu80p. However, it is not clear if localization of telomeres to the periphery actually contributes to TPE. We examined the localization patt...

BACKGROUND In comparison with many nuclear proteins, the movement of chromatin in nuclei appears to be generally constrained. These restrictions on motion are proposed to reflect the attachment of chromatin to immobile nuclear substructures. RESULTS To gain insight into the regulation of chromosome dynamics by nuclear architecture, we have followed the movements of different sites in the huma...

PURPOSE Magnetic resonance imaging (MRI) was used to map the refractive index distribution in human eye lenses in vivo and to investigate changes with age and accommodation. METHODS Whole-eye MR images were obtained for sagittal and transverse axial planes in one eye each of 15 young (19-29 years) and 15 older (60-70 years) subjects when viewing a far ( approximately 6 m) target and at indivi...

The paper develops an argument concerning the pluralistic character of the process of globalization, as contrasted with the conventional account that sees global processes creating uniformity and convergence. This alternative account is based on a series of case studies of latecomer and newcomer multinational corporations, such as Acer, Ispat International, Li & Fung and the Hong Leong Group; a...