abstract hypotonia is a serious neurologic problem in neonatal period. although hypotonia is a nonspecific clinical finding but it is the most common motor disorder in the newborn. the objective of this study was to determine the frequency of neonatal hypotonia then to ascertain of the most common causes methods this cross –sectional prospective study was carried out on the 3281 term infants ho...

introduction: repair of peripheral nerve injuries is an intensive area of challenge and research in modern reconstructive microsurgery. intensive research is being carried out to develop effective alternatives to the standard nerve autografting, avoiding its drawbacks. the aim of the study was to evaluate the effectiveness of a newly designed mechanical device for the reconstruction of the scia...

paclitaxel is a highly effective anticancer agent. it is active against a broad range of cancers that are generally considered refractory to conventional chemotherapy. paclitaxel induces a peripheral neuropathy (pn) that is characterized by sensory symptoms such as numbness and paresthesia in a glove and stocking distribution. pn may be severe and dose limiting at initial doses above 275 mg/m2....

The aim of this article is to provide an overview of peripheral vascular disease (PVD) and highlight the associated risk factors. Patient assessment and subsequent medical treatments will be reviewed. The role of the nurse will concentrate on health promotion and reduction in risk factors. After reading this article, you should be able to: ■ Define peripheral vascular disease and briefly outlin...

There is general agreement on peripheral factors of muscle fatigue that develop within the muscle and impair muscle fiber contractile mechanisms and muscle performance. Central factors of muscle fatigue that arise within the central nervous system have also been suggested to influence muscle force during fatigue. However, no direct empirical evidence of their influence on muscle force capacity ...

In a wounded nerve fiber, the distal segment separated from the nerve cell body, suffer an anterograde or Wallerian degeneration and within the proximal segment of the axon appear a retrograde or traumatic degeneration. The regeneration of peripheral nervous fibers is a complex process, with multiple interactions. The factors that are stimulating the regeneration of the peripheral nervous fiber...

many experimental studies have reported behavioral improvement after transplantation of peripheral nerve tissue into the contused spinal cord, even in large animals. the safety of this treatment in human remains unknown. in this translational phase 1 study, safety of peripheral nerve grafting for chronic spinal cord injuries and possible outcomes are being reported. twelve complete motor spinal...

mitochondria play key roles in many cell functions including energy production, fatty acid metabolism, pyrimidine biosynthesis, calcium homeostasis, and aging. they also regulate crucial signaling cascades such as apoptosis and oxidative stress. the proteome is often used to investigate the functional correlations on protein levels. based upon the human, genome there is estimated 2000 to 2500 a...

background : an elevation in the mean percentages of the gamma delta t lymphocytes per total t cells in the epithelium of the small intestine has a diagnostic value for celiac disease.  this study aimed to measure the percentages of the peripheral blood gamma delta t lymphocytes in the adults' celiac disease and healthy controls. materials and methods: in this case-control study the absolute nu...