Congenital syphilis is the oldest recognized congenital infection, and continues to account for extensive global perinatal morbidity and mortality today. Serious adverse pregnancy outcomes caused by maternal syphilis infection are prevented with screening early in pregnancy and prompt treatment of women testing positive. Intramuscular penicillin, an inexpensive antibiotic on the essential medic...

Human immunodeficiency virus (HIV) infection and hepatitis are common vertically transmitted diseases. Pregnant women infected with Hepatitis B virus represent a major reservoir of the virus in the community. Transmission of HBV from carrier mothers to their babies can occur during the perinatal period, and appears to be the most important factor in determining the prevalence of infection in hi...

The review considers some physiological features that reflect gender differences in the susceptibility to a novel coronavirus infection. Up-to-date information on impact of COVID-19 course pregnancy and perinatal outcomes is presented. debatable issues possibility vertical transmission SARS-CoV-2 virus are highlighted based analysis available literature data recommendations international profes...

Excess perinatal morbidity and mortality continue to be major problems in developed and developing nations. Most perinatal deaths occur in infants born weighing less than 2500 g. Large expenditures of time, equipment, and personnel have led to striking reductions in neonatal mortality. However, rates of prematurity have not declined. Exploration of proven causes of prematurity and low birth wei...

Across the placenta infections include Toxoplasma gondii, Treponema pallidum, Listeria monocytogenes, Plasmodium falciparum (malaria), rubella and cytomegalovirus (CMV). Ascending maternal infection and chorioamnionitis causing fetal infection, usually subsequent to prolonged rupture of membranes. Perinatal infection acquired during birth via the haematogenous or genital route. These include hu...

Across the placenta infections include Toxoplasma gondii, Treponema pallidum, Listeria monocytogenes, Plasmodium falciparum (malaria), rubella and cytomegalovirus (CMV). Ascending maternal infection and chorioamnionitis causing fetal infection, usually subsequent to prolonged rupture of membranes. Perinatal infection acquired during birth via the haematogenous or genital route. These include hu...

Across the placenta infections include Toxoplasma gondii, Treponema pallidum, Listeria monocytogenes, Plasmodium falciparum (malaria), rubella and cytomegalovirus (CMV). Ascending maternal infection and chorioamnionitis causing fetal infection, usually subsequent to prolonged rupture of membranes. Perinatal infection acquired during birth via the haematogenous or genital route. These include hu...

To what extent the risks of neonatal morbidities are directly related to premature birth or to biological mechanisms of preterm birth remains uncertain. We aimed to examine the effect of exposure to amniotic fluid (AF) infection and elevated cytokine levels on the mortality and pulmonary, intestinal, and neurologic outcomes of preterm infants, and whether these associations persist after adjust...

BACKGROUND There are conflicting results in the literature on the impact of chorioamnionitis on neonatal respiratory morbidities. However, most studies are based on small clinical samples and fail to account for the competing risk of perinatal death. This study aimed to determine whether chorioamnionitis affects the incidence of respiratory distress syndrome (RDS) and bronchopulmonary dysplasia...