background & target: ischemia reperfusion injury is the tissue damage caused when blood supply returns to the tissue after a period of ischemia or lack of oxygen. in this study, the effect of pentoxyfylline on bcl2 gene expression changes and cell injury in kidney of rat following ischemia reperfusion were evaluated.methods: in this experimental study, 20 male wistar rats with average weight of...

conclusions trauma induced by the tip of the catheter at the contact location with the lv wall in a patient with mild hypercoagulable state accounted for intracardiac thrombosis formation and its embolization to the brain and intestines. introduction coronary angiography can be complicated by some major complications such as stroke. case presentation we describe a patient who presented with hem...

conclusions continuous portal triade clamping (the pringle maneuver) during liver ischemia (30 and 45 minutes) in rabbits resulted in no ischemic change. increasing time of clamping to 30 minutes was safe in intermittent pringle maneuver. materials and methods in an experimental study, 20 new-zealand white rabbits were selected. in laparotomy, a blunt dissector was passed through the foramen of...

background in contemporary practice, acute mesenteric ischemia (ami) remains a serious cause of morbidity and mortality in abdominal emergencies. objectives we report the measurement of peritoneal fluid potassium and ph on a small series of rats that developed extensive ami following the surgical ligation of superior mesenteric vessels and compare the results with control groups. materials and ...

Renal ischemia–reperfusion (IR) is inevitable in partial nephrectomy and kidney transplantation. Acute tubular necrosis (ATN) induced by renal IR causes the loss of functional units kidney, pathologically presenting as nonhomogeneous distribution normal uriniferous tubules usually used to characterize activity. Optical coherence tomography (OCT) has been proven have ability image microstructure...

introduction: stroke is the third important reason of death in adults and an important cause of adult disability. previous studies suggest that tgf-alpha can induce neurogenesis after stroke. here in, we studied neurogenesis effects of the tgf-alpha on subventricular zone following ischemia-reperfusion. male wistar rats (250-300 g) were divided into ischemia and treatment groups. after inductio...

Objective: To compare the ocular surface changes following Femtosecond laser in situ keratomileusis (Femto-LASIK) and photorefractive keratectomy (PRK). Material Methods: TThis prospective study included 74 eyes of 37 patients: 34 were Femto-LASIK group, 40 PRK group. Schirmer test, tear break-up time, conjunctival impression cytology (CIC) used to determine before 1 month, 3 months after or Fe...

objective: oxygen free radicals may be implicated in the pathogenesis of ischemia reperfusion damage. the beneficial effects of antioxidant nutrients, as well as complex plant extracts, on cerebral ischemia-reperfusion injuries are well known. this study was conducted to determine the effects of the hydro-alcoholic root extract of withania coagulans on ca1 hippocampus oxidative damages followin...

  Background: It is well known that the hippocampus, the CA1 Pyramidal cells in particular, is selectively vulnerable during global cerebral ischemia. Recently, it is observed that pentoxifylline has a neuroprotective effect. This study explored the pharmacological relationship between ischemia-induced cell death of the hippocampus and the efficacy of a vasodilator agent (pentoxifylline) in the...