PURPOSE To report a specific line of research developed at the University of São Paulo/Brazil on fibrin glue used for sealing corneal perforations and the perspectives of use on non-perforated corneal ulcers and photorefractive keratectomy-operated corneas. METHODS To describe fibrin glue manufacture, development of a device to test the glued perforated corneal area resistance, subsequent exp...

BACKGROUND Delay in diagnosis and treatment of perforated appendicitis may cause life-threatening complications.The aim of this study was to determine and compare pre-operative total and direct bilirubin levels incases of simple and perforated acute appendicitis in order to improve the clinical decision making. METHODS This prospective observational study included eighty patients who underwen...

INTRODUCTION Gastrointestinal stromal tumours (GISTs) are the most common connective tissue neoplasms of the gastrointestinal tract, the most common clinical presentation of which is with abdominal pain or gastrointestinal bleeding. METHODS We describe a case of a perforated gastric GIST as well as reviewing the relevant published literature. RESULTS A 51-year-old woman presented to the acu...

PURPOSE This study evaluated the feasibility of a laparoscopic approach in children with generalized peritonitis secondary to perforated appendicitis. MATERIALS AND METHODS We retrospectively analyzed the medical records of patients who underwent laparoscopic appendectomy with drainage for generalized peritonitis secondary to perforated appendicitis at our hospital between September 2001 and ...

PURPOSE This study aimed to determine whether routine urinalysis may serve as a tool in discriminating between acute appendicitis and perforated appendicitis in children. BASIC PROCEDURES We prospectively collected 357 patients with clinically suspected acute appendicitis. Urinalysis was performed in patients with clinically suspected acute appendicitis before surgical intervention. Routine u...

PURPOSE Perforations are rare but serious complications of colorectal cancer, with mortality rates of 30 to 40 percent. The aim of this retrospective study was to investigate possible indicators of prognosis and causes of death and to evaluate the risk of this complication by comparing results in perforated tumors with uncomplicated cancers or large-bowel perforations attributable to benign cau...

Most models for predicting the acoustic response of perforated panels are based on the assumption that there is no interaction between the holes. The common way of taking into account the perforates effects is the use of Fok's functions. The few papers that deal with these effects study the case of low sound pressure levels. This paper investigates the Holes Interaction Effects (HIE) of perfora...

We present a methodology for the computation of flow fields involving complex perforated surfaces in propulsion applications. Of particular interest is the treatment of perforated flaps used as wedge-shaped fan flow deflectors for reducing jet noise of a supersonic turbofan engine. A three-dimensional Reynolds-Averaged Navier-Stokes solver is used to compute the flow field of the external jet p...

This work deals with the elastic and plastic properties of two-dimensional periodic metamaterials. Design maps are developed to ensure their isotropic response while attaining theoretical stiffness limits. Numerical simulations two different topologies - triangular round hole staggered patterns performed analyze large deformation for relative densities ranging from 0.1 0.9. The investigations s...

We consider the evolutionary compressible Navier-Stokes equations in a two-dimensional perforated domain, and show that subcritical case of very tiny holes, density velocity converge to solution non-perforated domain.