Stress in the diaphragm, transdiaphragmatic pressure, and diaphragm shape are interrelated by a balance of forces. Using precise in vivo measurements of diaphragm shape and transdiaphragmatic pressure distribution in combination with finite-element analysis (ANSYS), we determined the direction and magnitude of stress in the passive diaphragm at relaxation volume. Lead spheres sutured along musc...

A trisonic wind tunnel has been modified to improve its flow quality when operating at transonic speeds through perforated walls and side suctions. The usefulness of such a perforated wall, already known, is reduction of the blockage effect as well as the shock elimination. Two types of perforated walls have been used in this investigation. The first wall had a porosity of about 22% and the hol...

It is believed that the appendix will be perforated if the surgery of an acute appendicitis is delayed. However, some of the recent studies, contested this hypothesis and shown that only a delay in the treatment cannot fully explain perforated appendicitis. This study aimed to examine the prevalence and risk factors for perforated appendicitis in patients with acute appendicitis. A cross-sectio...

Ahn B, Beharry AW, Frye GS, Judge AR, Ferreira LF. NAD(P)H oxidase subunit p47 is elevated, and p47 knockout prevents diaphragm contractile dysfunction in heart failure. Am J Physiol Lung Cell Mol Physiol 309: L497–L505, 2015. First published July 24, 2015; doi:10.1152/ajplung.00176.2015.—Patients with chronic heart failure (CHF) have dyspnea and exercise intolerance, which are caused in part b...

The use of esophageal recordings of the diaphragm electromyogram (EMG) signal strength to evaluate diaphragm activation during voluntary contractions in humans has recently been criticized because of a possible artifact created by changes in lung volume. Therefore, the first aim of this study was to evaluate whether there is an artifactual influence of lung volume on the strength of the diaphra...

[Purpose] The purpose of this study was to examine effects of diaphragm breathing exercise applied on the basis overload principle on respiratory function. [Subjects and Methods] The subjects of this study were 35 normal adults. They were randomly assigned to two group; the maneuver-diaphragm exercise group and self-diaphragm exercise group. The respiratory function was evaluated using the Card...

Transmission spectra of thin metal films perforated by a high density of disordered sub-wavelength diameter cylindrical holes have been measured. The films, consisting of duplex layers of chromium and gold or chromium and silver, were characterised by perforations of mean diameter, hdi and fractional area coverage, F: films with hdi and F of 187F 50 nm and 0.21, and 340F 67 nm and 0.28 were stu...

PURPOSE Emergency operations for perforated peptic ulcer are associated with a high incidence of postoperative complications. While several studies have investigated the impact of perioperative risk factors and underlying diseases on the postoperative morbidity after abdominal surgery, only a few have analyzed their role in perforated peptic ulcer disease. The purpose of this study was to deter...

In congestive heart failure (CHF), diaphragm weakness is known to occur and is associated with myosin loss and activation of the ubiquitin-proteasome pathway. The effect of modulating proteasome activity on myosin loss and diaphragm function is unknown. The present study investigated the effect of in vivo proteasome inhibition on myosin loss and diaphragm function in CHF rats. Coronary artery l...

The effects of repairing the perforated sinus membrane with collagen membrane are unknown. The purpose of this pilot study was to clinically, histologically, and histomorphometrically evaluate the results of repairing the perforated sinus membrane with resorbable collagen membrane. A split-mouth design was followed in the current study. Five subjects requiring bilateral sinus grafting were incl...