Background. The therapeutic value of doxorubicin (DOX) is limited by its cardiotoxicity, which is dose dependent. To improve the detection of such myocardial damage, this study was designed to determine whether the "'In antimyosin antibody Fab could serve as a marker for cardiotoxicity in treated versus control rats on the basis of comparative morphological and hemodynamic findings. Methods and...

The purpose of the present work was to introduce 141Ce-EDTMP as a novel potential future pain palliative agent to patients suffering from disseminated skeletal metastases and diagnostic imaging radioisotope as well. Cerium-141 [T1/2 = 32.501 days, Eβ (max) = 0.580 (29.8%) and 0.435(70.2%) MeV, Eγ = 145.44 (48.2%) keV] possesses radionuclidic properties suitable for use in palliative therapy of ...

Bacteria injected into the bloodstream of guinea pigs shortly before death decreased in number in carcass tissues for about 1 h after death. If initial bacterial numbers were sufficiently low, all bacteria were eliminated, and carcass tissues were sterile 24 h after death. Carcass tissue sterility was maintained with an initial density of Clostridium perfringens or Salmonella typhimurium of 20 ...

background: the shielding methods in radiotherapy due to delivering an accurate radiation dose to cancer tissues and avoiding unnecessary dose to normal tissues are very important. these methods include lead standard blocks, individual molding and multi leaf collimator (mlc). the mlc method is not still common in iran radiotherapy centers. individual molding is better than the lead block shield...

this experiment was carried out at agricultural research station of gorgan during summer 2006 to study the effects of corn and green gram intercropping on forage yield, and weed biomass. the experimental design was rcbd with twelve treatments and four replications. a local green gram and corn single cross 550 were the crops employed. the experimental treatments consisted of sole corn and sole g...

Glucose oxidase, covalently coupled to polystyrene microspheres (GOL), produced H(2)0(2) at an average rate of 3.6 nmol/min per 10(9) beads under standard assay conditions. Injection of 1.3 x 10(10) to 1.1 x 10(11) GOL i.p. prolonged the survival of mice by 27 percent after injection of 10(6) P388 lymphoma cells in the same site, consistent with destruction of 97.6 percent of the tumor cells. P...

The localization of i.p. injected, radioiodine conjugated monoclonal antibody HMFG2 was studied in 18 patients with ovarian carcinoma. Patients were injected i.p. at time points up to 168 h before laparotomy, at which time tumor, ascites, normal tissue, and blood samples were removed and the contained radioactivity measured. In the first 10 patients, localization was compared with that of a sim...

When cotton linters were soaked in cold 10-percent sodium hydroxide, washed, a nd neutralized, and transferred successively to methyl alcohol and benzene, and carefully dried a t reduced pressure, a surface area as high as 71.3 square meters per gram was obtained by the Brunauer , Emmett, T e ller technique. Previous areas for untreated cotton were a ll below 1 sq uare meter per gram. Linters c...

Saline extracts of homogenized, uninfected, rabbit tissues produced febrile responses when injected intravenously into rabbits. Extracts of muscle, lung, and heart evoked fevers that were similar to those induced by leucocyte pyrogen; extracts of spleen, liver, and kidney caused more sustained fevers. The minimal pyrogenic dose appeared to be between 1.5 and 3 gm wet weight of tissue. Evidence ...