Journal:
:iranian journal of basic medical sciences
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tamara aghebati nanotechnology research center, mashhad university of medical sciences, mashhad, iran
amir hooshang mohammadpour pharmaceutical research center, mashhad university of medical sciences, mashhad, iran
mohammad afshar department of anatomy, faculty of medicine, birjand university of medical sciences, birjand, iran
medical toxicology research centre, mashhad university of medical sciences, mashhad, iran
mahmoud reza jaafari biotechnology research center, mashhad university of medical sciences, mashhad, iran
khalil abnous pharmaceutical research center, mashhad university of medical sciences, mashhad, iran
objective(s): in this study, for the first time, mf59 adjuvant was used to develop a cholesteryl ester transfer protein (cetp) vaccine. the efficacy of the vaccine was compared with the efficacy of cetp vaccine formulated with alum/cpg, the formulation that its immunogenicity has been already demonstrated in rabbit and mice. materials and methods: tetanus toxoid- cetp peptide (tt-cetp) was mixe...