The aim of the present study was to compare deep lamellar endothelial keratoplasty (DLEK) and penetrating keratoplasty (PK) treatments for bullous keratopathy (BK). In total, 36 healthy New Zealand white rabbits were randomly divided into 3 groups termed the experimental, DLEK and PK groups. The experimental control group received no treatment. The DLEK and PK groups were observed for corneal a...

BACKGROUND Corneal ulcers often lead to scarring and astigmatism, and significant loss of vision is a common consequence. OBJECTIVE To determine the rate of graft rejection, one of the most serious concerns with this procedure, and to evaluate the recovery of visual function in those patients for whom the operation was successful. METHODS We describe a retrospective study of 33 corneal ulce...

Purpose: The feasibility of standardized treatment for fungal keratitis was explored through the analysis of results. Methods: The medical records of 508 hospitalized patients with fungal keratitis in Qingdao eye hospital of Shandong province eye institute from January 2008 to December 2012 were analyzed in this retrospective study. Results: Among total 508 cases (all simple eye), 21 cases (4.1...

PURPOSE To test the hypothesis that a new microkeratome-assisted penetrating keratoplasty (PK) technique employing transplantation of a two-piece mushroom-shaped graft may result in better visual outcomes and graft survival rates than those of conventional PK. METHODS Retrospective chart review of 96 eyes at low risk and 76 eyes at high risk for immunologic rejection (all with full-thickness ...

Penetrating keratoplasty is the replacement of a diseased cornea with a full-thickness donor graft. In the last century, this 'gold standard' procedure was long established as the treatment of choice for various corneal diseases. The classical indications for a penetrating keratoplasty entailed optical, tectonic, therapeutic, and cosmetic issues. Over the past decade however, surgical advances ...

PURPOSE To report the clinical outcomes of deep anterior lamellar keratoplasty (DALK) when sterile gamma-irradiated acellular corneal tissues (VisionGraft) are used in combination with amniotic membrane transplantation (AMT) for intractable ocular surface diseases. METHODS The medical records of fifteen patients who had DALK with AMT were retrospectively reviewed. Indications for surgery incl...

purpose: to evaluate changes in graft steepness after graft refractive surgery (grs) and to discover influential factors and a coefficient to predict the amount of postoperative shift. methods: keratoconic patients with history of penetrating keratoplasty (pkp) who underwent grs due to high post-pkp astigmatism were included. changes in mean keratometry after grs were evaluated to find possible...

in addition to graft clarity, an acceptable refractive error is essential to consider a corneal transplant successful. the most common complication of penetrating keratoplasty (pk) is postkeratoplasty astigmatism which can result in decreased visual acuity, anisometropia, and mono-ocular diplopia. these complications can cause patient dissatisfaction, in spite of a successful transplant. intrao...

The purpose of this study was to compare the effects on astigmatism after penetrating keratoplasty with three different suture techniques. In this prospective study, 38 eyes of 38 patients underwent penetrating keratoplasty with three suturing techniques: interrupted, single running, and double running. Topographic astigmatism was measured at 2, 6, 12, and 18 months after keratoplasty. During 1...

PURPOSE Cytokine patterns in the aqueous humor before penetrating keratoplasty might permit us to predict the development of immune reactions. We therefore analyzed ten different cytokines in the aqueous humor of patients before and following penetrating keratoplasty. METHODS We collected aqueous humor from patients undergoing cataract extraction or penetrating keratoplasty (baseline, n=197),...